Meglumine impurity 8 CAS 24758-59-6
| CAS No. | 24758-59-6 |
| Molecular Formula | C7H15NO6 |
| Molecular Weight | 209.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Meglumine impurity 8 is closely related to a carbohydrate-derived structure, an amide group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Meglumine impurity 8 (CAS 24758-59-6, C7H15NO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Meglumine impurity 8 (C7H15NO6) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Meglumine impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H15NO6 |
| Molecular Weight | 209.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Meglumine Standards
- Meglumine Impurity 5 (CAS 10356-92-0)
- Meglumine impurity 6 (CAS 62137-31-9)
- Meglumine Impurity 24 (CAS CATO-C4X-21424)
- Meglumine impurity 9 (CAS 158808-56-1)
- Meglumine Metrizoate (CAS 7241-11-4)
- Meglumine Impurity 10 (CAS CATO-C4X-214210)
- Meglumine Impurity 12 (CAS CATO-C4X-214212)
- Meglumine Impurity 13 (CAS CATO-C4X-214213)
Recommended Standards
- Vilanterol Impurity 45 (CAS CATO-C4X-193545)
- Tivozanib Impurity 21 (CAS CATO-C4X-340021)
- Urapidil Impurity 104 (CAS CATO-C4X-1924104)
- Dimethyl Aminoterephthalate (CAS 5372-81-6)
- CAS CATO-C3D-262787 (CAS CATO-C3D-262787)
- Cefdinir Impurity 38 (CAS 37155-50-3)
- Amorolfine Impurity 91 (CAS CATO-C4X-154291)
- 1-Chloro-2-propanol Phosphorochloridate (CAS 13674-83-4)
- Ethyl 2-amino-4,5-difluorobenzoate (CAS 864293-36-7)
- 4-((4-Methoxyphenyl)diazenyl)-1H-pyrazole-3,5-diamine (CAS 6975-75-3)
- 1-(3,4-Dimethoxybenzyl)-4-hydroxy-6-methylpyridin-2(1H)-one (CAS 758700-59-3)
- 2-(2-(Phenylcarbamoyl)hydrazine-1-carbonyl)benzoic acid (CAS 302604-71-3)
- 4-(Piperazin-1-ylmethyl)benzene-1,2-diol (CAS 1178067-02-1)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com