7-Fluoro-3-iodo-6-methoxy-1H-indazole CAS 2484889-00-9
| CAS No. | 2484889-00-9 |
| Molecular Formula | C8H6FIN2O |
| Molecular Weight | 292.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Fluoro-3-iodo-6-methoxy-1H-indazole.
CATO supplies 7-Fluoro-3-iodo-6-methoxy-1H-indazole (CAS 2484889-00-9), a certified reference material (molecular formula C8H6FIN2O, MW 292.05 g/mol) for analytical method development and quality control.
The molecular framework of 7-Fluoro-3-iodo-6-methoxy-1H-indazole (C8H6FIN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Fluoro-3-iodo-6-methoxy-1H-indazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6FIN2O |
| Molecular Weight | 292.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-Fluoro-3-iodo-7-methoxy-1H-indazole (CAS 1000342-15-3)
- 3-(2-Fluoro-5-iodophenyl)acrylic acid (CAS 773130-25-9)
- 4-Fluoro-3-iodo-6-methoxy-1H-indazole (CAS 887569-17-7)
- 2-Fluoro-3-iodo-6-(pyrrolidin-1-yl)pyridine (CAS 1203499-32-4)
- 2-Fluoro-4-iodo-6-(pyrrolidin-1-yl)pyridine (CAS 1228665-69-7)
- (E)-3-(2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylic acid (CAS 1001200-58-3)
- 2-Fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)cinnamic acid (CAS 2377612-53-6)
- 3-Fluoro-4-(4-methoxybenzylthio)phenylboronic acid (CAS 1072946-13-4)
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- 6-(3-Nitrophenyl)picolinic Acid (CAS 80021-34-7)
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- 4-Methylbenzotriazole (CAS 29878-31-7)
- 3-(Benzo[d][1,3]dioxol-5-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine-6-carboxylic acid (CAS 126598-35-4)
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