Tert-butyl 4-(benzyloxy)-3,5-dichlorobenzoate CAS 2484889-07-6
| CAS No. | 2484889-07-6 |
| Molecular Formula | C18H18Cl2O3 |
| Molecular Weight | 353.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-(benzyloxy)-3,5-dichlorobenzoate (CAS 2484889-07-6), molecular formula C18H18Cl2O3 and molecular weight 353.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Tert-butyl 4-(benzyloxy)-3,5-dichlorobenzoate (C18H18Cl2O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18Cl2O3 |
| Molecular Weight | 353.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Recommended Standards
- tert-butyl (4R)-4-(2-iodoethyl)-2,2-dimethyl-pyrrolidine-1-carboxylate (CAS 2609741-00-4)
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- 2,4,4',6-Tetramethylbenzophenone (CAS 1146-84-5)
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- 4-Amino-6-cyano-5-(trifluoromethoxy)pyridine-2-sulfonyl chloride (CAS 1806001-01-3)
- 5-Ethylpicolinimidamide hydrochloride (CAS 1179361-64-8)
- semaglutide (CAS 782487-28-9)
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