6-Chloro-5-iodopyridazin-4-amine CAS 2490407-06-0
| CAS No. | 2490407-06-0 |
| Molecular Formula | C4H3ClIN3 |
| Molecular Weight | 255.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 255.44 g/mol gives 6-Chloro-5-iodopyridazin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-5-iodopyridazin-4-amine (CAS 2490407-06-0) is a high-purity analytical reference standard with the molecular formula C4H3ClIN3 and a molecular weight of 255.44 g/mol.
The molecular framework of 6-Chloro-5-iodopyridazin-4-amine (C4H3ClIN3) is characterized by a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-5-iodopyridazin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3ClIN3 |
| Molecular Weight | 255.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-4-iodopyridin-3-ol (CAS 1207973-15-6)
- 6-Chloro-3-iodopyridin-2-ol (CAS 1224719-11-2)
- 2-Chloro-5-iodopyridin-4-ol (CAS 1226878-99-4)
- 2-Chloro-3-iodopyridin-4-ol (CAS 1226879-01-1)
- 3-Chloro-4-iodopyridin-2-ol (CAS 1227514-51-3)
- 3-Chloro-5-iodopyrazin-2-amine, 97% (CAS 1252597-70-8)
- 5-Chloro-4-iodopyrimidin-2-amine (CAS 1260863-63-5)
- 4-Chloro-5-iodopyridin-2-ol (CAS 1628557-08-3)
Recommended Standards
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