(5-Chloropyridin-3-yl)dimethylphosphine oxide CAS 2490420-74-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2490420-74-9
Molecular FormulaC7H9ClNOP
Molecular Weight189.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5-Chloropyridin-3-yl)dimethylphosphine oxide CAS 2490420-74-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (5-Chloropyridin-3-yl)dimethylphosphine oxide.

(5-Chloropyridin-3-yl)dimethylphosphine oxide (CAS 2490420-74-9) is a high-purity analytical reference standard with the molecular formula C7H9ClNOP and a molecular weight of 189.58 g/mol.

Owing to an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage, chlorine substitution, (5-Chloropyridin-3-yl)dimethylphosphine oxide is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 189.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (5-Chloropyridin-3-yl)dimethylphosphine oxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H9ClNOP
Molecular Weight189.58 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)2000
Halogen ContentCl-containing
Nitrogen Atoms1

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