4-((Difluoromethyl)sulfonyl)phenol CAS 24906-81-8
| CAS No. | 24906-81-8 |
| Molecular Formula | C7H6F2O3S |
| Molecular Weight | 208.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-((Difluoromethyl)sulfonyl)phenol (CAS 24906-81-8), molecular formula C7H6F2O3S and molecular weight 208.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-((Difluoromethyl)sulfonyl)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-((Difluoromethyl)sulfonyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6F2O3S |
| Molecular Weight | 208.18 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 5-{[(difluoromethyl)thio]methyl}-2-furoic acid (CAS 1000932-45-5)
- 2-{[(difluoromethyl)sulfanyl]methyl}furan-3-carboxylic acid (CAS 1000932-75-1)
- 2-((Difluoromethyl)sulfonyl)phenol (CAS 1240527-67-6)
- Methyl 5-(difluoromethyl)-3-hydroxythiophene-2-carboxylate (CAS 181313-01-9)
- Ethyl 4-(difluoromethyl)-1,2,3-thiadiazole-5-carboxylate (CAS 1018170-57-4)
- 7-(Difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 512823-59-5)
- 2-(Difluoromethyl)-6-methoxynaphthalene (CAS 1261468-45-4)
- 2-(Difluoromethyl)naphthalene-8-methanol (CAS 1261470-14-7)
Recommended Standards
- 3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro[4.5]Dec-2-ene (CAS 2091398-00-2)
- 4-(trifluoromethyl)-1,3-dihydrobenzimidazol-2-one (CAS 2251-78-7)
- 3-(3,3,3-Trifluoro-2,2-dimethylpropoxy)-1H-pyrazole (CAS 2229861-15-6)
- 4-(trifluoromethyl)norbornane-1-carboxylic acid (CAS 952403-55-3)
- Tert-butyl 5-fluoro-1-oxa-7-azaspiro[3.5]Nonane-7-carboxylate (CAS 2387176-80-7)
- 4-Bromo-5-ethoxy-2-nitroaniline (CAS 1242336-59-9)
- Nonadienal (CAS 30551-17-8)
- 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol (CAS 26495-07-8)
- 2-Chloro-3-[4-(3-methylpiperidine-1-carbonyl)piperidin-1-yl]-1,4-dihydronaphthalene-1,4-dione (CAS 439108-69-7)
- Methyl 2-(4-(N-cyclopropylsulfamoyl)phenoxy)acetate (CAS 696632-85-6)
- 5-Fluoropyridine-2-carboxaldehyde (CAS 31181-88-1)
- 0126AD 1185077-23-9 4-[(2-Methyl-2-propenyl)oxy]piperidine hydrochloride C9H18ClNO (CAS 1185077-23-9)
- Butyl 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetate (CAS 1797030-15-9)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
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