2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole CAS 2491-90-9
| CAS No. | 2491-90-9 |
| Molecular Formula | C14H8Cl2N2O |
| Molecular Weight | 291.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole (C14H8Cl2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole (CAS 2491-90-9), molecular formula C14H8Cl2N2O and molecular weight 291.13 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,5-Bis(4-chlorophenyl)-1,3,4-oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2N2O |
| Molecular Weight | 291.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2,5-Bis-(3-chlorophenyl)-1,3,4-oxadiazole (CAS 2639-17-0)
- Bis(3-chlorophenyl)-1H-1,2,3,4-tetrazole (CAS 338411-24-8)
- 1-[(4-chlorophenyl)methyl]-1h-pyrazole-4-sulfonyl chloride (CAS 1179625-82-1)
- 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-sulfonyl chloride (CAS 1291374-78-1)
- 2,2-Bis(4-chlorophenyl)cyclopropanecarbaldehyde (CAS 65498-79-5)
- 3,5-Bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazole (CAS 50800-82-3)
- Bis[(3-chlorophenyl)methyl](cyano)amine (CAS 866048-83-1)
- 1-(2-Chlorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-48-1)
Recommended Standards
- 2,6-Dichloro-3-phenylquinazolin-4(3H)-one (CAS 31797-22-5)
- 2-(3,4-Dichlorophenyl)quinazolin-4(1H)-one (CAS 285988-42-3)
- 2-Chloro-2-(4-chlorophenyl)-1H-indene-1,3(2H)-dione (CAS 730-74-5)
- 2-(2,4-Dichlorophenyl)quinazolin-4(1H)-one (CAS 83800-89-9)
- tert-Butyl (R)-(2,5-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)carbamate (CAS 1227261-70-2)
- (+/-)-1-(4- Bromophenyl)Ethylamine (CAS 27298-97-1)
- 1,3-Dimethyl-5,6,7,8-tetrahydroisoquinoline (CAS 65818-00-0)
- 3-Methylfuran-2-carbohydrazide (CAS 52541-78-3)
- 3-Chloro-4-(1,1,2-trifluoro-2-(trifluoromethoxy)ethoxy)aniline (CAS 116714-47-7)
- Dimethyl 4-(4-aminophenyl)-2,6-dimethylpyridine-3,5-dicarboxylate (CAS 887407-34-3)
- 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-4-phenylbutanoicacid (CAS 885274-45-3)
- 2-Bromo-6-(difluoromethyl)-4-methoxynicotinonitrile (CAS 1805357-91-8)
- Acid-PEG3-PFP ester (CAS 1835759-67-5)
- Peptide WE-14 (CAS 115136-18-0)
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