2-(2,5-Dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepin-3-yl)acetic acid CAS 24919-38-8
| CAS No. | 24919-38-8 |
| Molecular Formula | C11H10N2O4 |
| Molecular Weight | 234.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(2,5-Dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepin-3-yl)acetic acid (CAS 24919-38-8), molecular formula C11H10N2O4 and molecular weight 234.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,5-Dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepin-3-yl)acetic acid (C11H10N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-(2,5-Dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepin-3-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10N2O4 |
| Molecular Weight | 234.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 2 |
Related Dioxo Standards
- 2-(4-Methyl-2,3-dioxo-3,4-dihydroquinoxalin-1(2H)-yl)acetic acid (CAS 1031628-34-8)
- Methyl 2-(2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)acetate (CAS 112342-46-8)
- 2-(2,4-Dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)acetohydrazide (CAS 1206154-66-6)
- ethyl 2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-carboxylate (CAS 1207175-71-0)
- 2-[(3s)-2,5-dioxo-2,3,4,5-tetrahydro-1h-1,4-benzodiazepin-3-yl]acetic acid (CAS 1217715-92-8)
- (R)-2-(2,5-dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-3-yl)acetic acid (CAS 1217717-66-2)
- Ethyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate (CAS 1268865-77-5)
- 4-{1,3-dioxo-1h,2h,3h-pyrrolo[3,4-c]pyridin-2-yl}butanoic acid (CAS 1322604-76-1)
Recommended Standards
- 2-(1-Methyl-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)acetic acid (CAS 55558-97-9)
- 2-(2,5-Dioxo-4-phenylimidazolidin-1-yl)acetic acid (CAS 212333-90-9)
- 2-((5-Nitrofuran-2-yl)methoxy)aniline (CAS 88796-65-0)
- 2-(2-Methyl-5-(1H-tetrazol-1-yl)phenoxy)acetic acid (CAS 924859-17-6)
- (E)-Ceftriaxone Disodium (CAS 97164-54-0)
- (1R,4S)-4-methoxycyclopent-2-en-1-ol (CAS 194606-96-7)
- Methyl 2-{3-[3-(benzyloxy)phenyl]phenyl}acetate (CAS 672932-31-9)
- 3-(3-Fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1402232-99-8)
- tert-Butyl (6-(bromomethyl)pyridin-2-yl)carbamate (CAS 400781-16-0)
- (Z)-4,6-Dihydroxy-2-(3,4,5-trihydroxybenzylidene)benzofuran-3(2H)-one (CAS 3260-50-2)
- 2-Amino-2-(1-(tert-butoxycarbonyl)-5-methylpiperidin-3-yl)acetic acid (CAS 2292381-04-3)
- 2-(2-Bromophenoxy)-5-fluoroaniline (CAS 1019583-99-3)
- 2-(3,3-Difluorocyclobutyl)ethylamine Hydrochloride (CAS 1427173-51-0)
- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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