5-(P-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-amine CAS 2492335-51-8
| CAS No. | 2492335-51-8 |
| Molecular Formula | C11H10F3N3 |
| Molecular Weight | 241.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(P-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-amine.
CATO supplies 5-(P-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-amine (CAS 2492335-51-8), a certified reference material (molecular formula C11H10F3N3, MW 241.21 g/mol) for analytical method development and quality control.
The molecular framework of 5-(P-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-amine (C11H10F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10F3N3 |
| Molecular Weight | 241.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related P Standards
- 4-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazol-3-amine (CAS 1136835-67-0)
- 3-(o-Tolyl)benzo[d]isoxazole-5,6-diol (CAS 105679-44-5)
- 3-(p-Tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-diamine (CAS 50307-55-6)
- 2-(p-Tolyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1355226-93-5)
- 2-(1-(p-Tolyl)-1H-pyrazol-5-yl)thiazole (CAS 1269293-89-1)
- 1-m-Tolyl-1H-benzoimidazole-2-thiol (CAS 438031-49-3)
- 6-(o-Tolyl)benzo[d]thiazol-2-amine (CAS 2436720-41-9)
- 8-(p-Tolyl)-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine (CAS 956432-31-8)
Recommended Standards
- 5-(3,3,3-Trifluoropropyl)quinolin-8-ol (CAS 660852-51-7)
- 5-[2-(Trifluoromethyl)phenyl]-1H-pyrrole-3-methanol (CAS 881674-62-0)
- 4-Methoxy-2-methyl-7-(trifluoromethyl)quinoline (CAS 881932-89-4)
- 5-Amino-3-methyl-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole (CAS 205127-44-2)
- 4-tert-Butyl 5-methyl 2-bromo-4H-thieno[3,2-b]pyrrole-4,5-dicarboxylate (CAS 1807542-86-4)
- 4-hydrazinyl-2-methylpyridine hydrochloride (CAS 1274887-18-1)
- 4-((4-Methoxyacridin-9-yl)amino)-N-(pyrimidin-2-yl)benzenesulfonamide (CAS 827025-28-5)
- 2-Phenoxy-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)propanamide (CAS 1208926-26-4)
- 1-((4-Methyl-1,4-diazepan-1-yl)methyl)cyclopentan-1-ol (CAS 1492491-97-0)
- 1-Methyl-4-phenylimidazolidine (CAS 95646-38-1)
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- Calcium Dobesilate impurity 18 (CAS CATO-C4X-205118)
- 5-Ethoxy-4-methoxy-2-nitrobenzaldehyde (CAS 15937-14-1)
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