1-(5-Chloro-2-hydroxyphenyl)pyrrolidine-2,5-dione CAS 249277-71-2
| CAS No. | 249277-71-2 |
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Chloro-2-hydroxyphenyl)pyrrolidine-2,5-dione (C10H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(5-Chloro-2-hydroxyphenyl)pyrrolidine-2,5-dione (CAS 249277-71-2) is a high-purity analytical reference standard with the molecular formula C10H8ClNO3 and a molecular weight of 225.63 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(5-Chloro-2-hydroxyphenyl)pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate (CAS 100478-04-4)
- 5-(5-chloro-2-methoxyphenyl)-1,3,4-oxadiazol-2-amine (CAS 1016686-46-6)
- Ethyl 5-chloro-3H-imidazo[4,5-b]pyridine-2-carboxylate (CAS 1044772-75-9)
- Ethyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1060816-62-7)
- ethyl 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate (CAS 1083181-27-4)
- 5-Chloro-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 112734-83-5)
- Methyl 4-chloro-2-cyano-5-methoxybenzoate (CAS 1138220-78-6)
- Methyl 6-chloro-8-methylimidazo[1,2-b]pyridazine-3-carboxylate (CAS 1150566-87-2)
Recommended Standards
- 1-(4-Nitrophenyl)cyclopropanecarbonyl chloride (CAS 422280-36-2)
- 2-(2-Chloroethoxy)isoindoline-1,3-dione (CAS 59376-93-1)
- (Z)-4-((2-chlorophenyl)amino)-4-oxobut-2-enoic acid (CAS 53616-16-3)
- 2-(4-Chlorophenyl)-5-imino-2,5-dihydrofuran-3,4-diol (CAS 7342-16-7)
- 2,6-Dimethoxy-benzylamine Hydrochloride 34967-23-2 (CAS 34967-23-2)
- 4-Butyl-1-oxa-4,9-diazaspiro[5.5]undecane (CAS 1707379-03-0)
- 5-Isopropylthiophen-2-amine (CAS 106971-18-0)
- 1-(Tetrahydro-2H-pyran-4-yl)propan-1-ol (CAS 854697-48-6)
- 1-(thiophen-2-ylmethyl)-1H-pyrrole (CAS 59303-11-6)
- (2E)-3-{[4-(phenylamino)phenyl]amino}-2-(1H-1,2,3,4-tetrazol-5-yl)prop-2-enenitrile (CAS 683799-78-2)
- 3,3',5,5'-Tetrabromo-2,2'-bithiophene (CAS 125143-53-5)
- Ethyl 4-acetamido-6-fluoroquinoline-3-carboxylate (CAS 1352541-61-7)
- Methyl 4-acetoxy-3-iodobenzoate (CAS 1131614-03-3)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com