3-((Difluoromethyl)thio)aniline CAS 24933-59-3
| CAS No. | 24933-59-3 |
| Molecular Formula | C7H7F2NS |
| Molecular Weight | 175.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-((Difluoromethyl)thio)aniline (C7H7F2NS) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-((Difluoromethyl)thio)aniline (CAS 24933-59-3), molecular formula C7H7F2NS and molecular weight 175.20 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7F2NS |
| Molecular Weight | 175.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 2-[(Difluoromethyl)sulfanyl]aniline (CAS 24933-58-2)
- 4-((Difluoromethyl)thio)aniline (CAS 24933-60-6)
- (R)-1-(3-(Difluoromethyl)-1-methyl-1H-pyrazol-4-yl)ethanamine (CAS 2227642-21-7)
- 4-(Difluoromethyl)bicyclo[2.2.2]octan-1-amine (CAS 1245643-16-6)
- 4-(Difluoromethyl)-5-(fluoromethyl)-2-methylpyridine (CAS 1804691-98-2)
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- 3-(Difluoromethyl)-1-methylpyrazole-4-carboxamide (CAS 925689-10-7)
Recommended Standards
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- 2-Fluoro-2-phenylcyclopropane-1-carboxylic acid (CAS 914221-42-4)
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