8-chloro-2-methoxy-1,5-naphthyridine CAS 249889-68-7
| CAS No. | 249889-68-7 |
| Molecular Formula | C9H17ClN2O |
| Molecular Weight | 204.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-chloro-2-methoxy-1,5-naphthyridine (CAS 249889-68-7), molecular formula C9H17ClN2O and molecular weight 204.70 g/mol, is a CATO reference standard with documented purity and traceability.
8-chloro-2-methoxy-1,5-naphthyridine (C9H17ClN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H17ClN2O |
| Molecular Weight | 204.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- (R)-tert-Butyl 1-ethylpyrrolidin-3-ylcarbamate (CAS 1286207-10-0)
- N-Methoxy-N-methyl-3-piperidinecarboxamide hydrochloride (CAS 1177353-95-5)
- [1-(3-methoxyphenyl)propyl](methyl)amine (CAS 941256-14-0)
- 4-((6-Aminoquinazolin-4-yl)amino)phenol (CAS 1428063-82-4)
- Lercanidipine Impurity 74 (CAS CATO-C4X-136474)
- 6-Chloro-3-hydrazinyl-4-methylpyridazine (CAS 66530-55-0)
- N1,N4-Bis(4-cyanophenyl)terephthalamide (CAS 69489-60-7)
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