2-Amino-5-(3-((4-(2-(2-(chloromethyl)-1,3-dioxolan-2-yl)ethyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one CAS 2499-43-6
| CAS No. | 2499-43-6 |
| Molecular Formula | C20H27ClN4O3 |
| Molecular Weight | 406.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-Amino-5-(3-((4-(2-(2-(chloromethyl)-1,3-dioxolan-2-yl)ethyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (CAS 2499-43-6), a certified reference material (molecular formula C20H27ClN4O3, MW 406.91 g/mol) for analytical method development and quality control.
The molecular framework of 2-Amino-5-(3-((4-(2-(2-(chloromethyl)-1,3-dioxolan-2-yl)ethyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one (C20H27ClN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2-Amino-5-(3-((4-(2-(2-(chloromethyl)-1,3-dioxolan-2-yl)ethyl)phenyl)amino)propyl)-6-methylpyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H27ClN4O3 |
| Molecular Weight | 406.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- 6-(2H-Benzo[e][1,3]oxazin-3(4H)-yl)-N2-(3-(triethoxysilyl)propyl)-1,3,5-triazine-2,4-diamine (CAS CATO-CIM-105738)
- 3,4-Dihydroxybenzophenone (CAS 10425-11-3)
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- 2-Chloro-3-(4-fluorophenyl)pyrazine (CAS 1094461-27-4)
- 4,4′-Dihydroxybiphenyl-d8 (rings-d8) (CAS 612480-60-1)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
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