6-Methylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione CAS 2499-96-9
| CAS No. | 2499-96-9 |
| Molecular Formula | C8H7N3O2 |
| Molecular Weight | 177.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Methylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Methylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 2499-96-9) is a high-purity analytical reference standard with the molecular formula C8H7N3O2 and a molecular weight of 177.16 g/mol.
6-Methylpyrido[3,2-d]pyrimidine-2,4(1H,3H)-dione (C8H7N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7N3O2 |
| Molecular Weight | 177.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Methylpyrido Standards
- 1-Methylpyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione (CAS 142168-85-2)
- 7-Methylpyrido[2,3-b]pyrazine-2,3-diol (CAS 144435-02-9)
- 1-Methylpyrido[2,3-b]pyrazine-2,3(1H,4H)-dione (CAS 67074-71-9)
- 7-Methylpyrido[2,3-d]pyrimidine-2,4-diol (CAS 36075-35-1)
- 2-Methylpyrido[2,3-b]pyrazine-3(4H)-thione (CAS 115366-84-2)
- 8-Methylpyrido[2,3-d]pyridazine-5-thiol (CAS 1330754-39-6)
- 2-methylpyrido[2,3-b]pyrazin-3-amine (CAS 1258652-12-8)
- 2-Methylpyrido[4,3-d][1,3]oxazin-4-one (CAS 3810-23-9)
Recommended Standards
- 6-Methyl-pyrazolo[1,5-α]pyrimidine-3-carboxylic Acid (CAS 869941-96-8)
- 6-Nitro-1H-indol-4-amine (CAS 885520-44-5)
- 6-Methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 889939-98-4)
- 6-Nitro-1-indanone (CAS 24623-24-3)
- 2-(1,4-Bis((benzyloxy)carbonyl)piperazin-2-yl)acetic acid (CAS 1698026-84-4)
- Sarizotan Impurity 2 (CAS 177976-33-9)
- n-Propyl-2,2,3,3,3-d5-amine (CAS 1398066-17-5)
- 6-cyclopropyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1315612-15-7)
- Mutaprodenafil (CAS 1387577-30-1)
- 5-Pentylisoxazole-3-carboxylic acid (CAS 89967-39-5)
- 2-[2-(4-methylphenyl)-1,3-thiazol-4-yl]Ethylamine (CAS 871689-46-2)
- tert-butyl (2S,5S)-2,5-dimethylpiperazine-1-carboxylate (CAS 1238951-37-5)
- Ethyl 3-(2-fluoropyridin-3-yl)propanoate (CAS 1820641-58-4)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com