(5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl)(3-(2,3-dihydroxypropoxy)phenyl)methanone CAS 249937-52-8
| CAS No. | 249937-52-8 |
| Molecular Formula | C19H18FN3O4 |
| Molecular Weight | 371.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl)(3-(2,3-dihydroxypropoxy)phenyl)methanone (CAS 249937-52-8), a certified reference material (molecular formula C19H18FN3O4, MW 371.36 g/mol) for analytical method development and quality control.
Structurally, (5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl)(3-(2,3-dihydroxypropoxy)phenyl)methanone (C19H18FN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 371.36 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18FN3O4 |
| Molecular Weight | 371.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- N6-(4-Amino-1-β-D-Ribofuranosyl-2(1H)-Pyrimidinylidene)-L-Lysine (CAS 144796-96-3)
- 1-Amino-4-(benzo[d]thiazol-2-ylamino)anthracene-9,10-dione (CAS 62593-01-5)
- 1-Amino-4-((3-((dimethylamino)methyl)phenyl)amino)anthracene-9,10-dione (CAS 83968-84-7)
- 1-Amino-4-(4-butylphenoxy)anthracene-9,10-dione (CAS 92002-94-3)
- 2-((4-Amino-5-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 763114-90-5)
- 2-Amino-1-(4-(tert-butyl)phenoxy)anthracene-9,10-dione (CAS 68256-56-4)
- methyl 3-amino-4-((4-isopropoxy-2-methylphenyl)amino)thieno[2,3-b]pyridine-2-carboxylate (CAS 2102410-70-6)
- 2-Amino-4-(4-bromophenyl)-5-(ethylsulfonyl)thiophene-3-carbonitrile (CAS 1708179-10-5)
Recommended Standards
- 5-(Benzyloxy)-3-((benzyloxy)carbonyl)-3-hydroxy-5-oxopentanoic acid (CAS 184834-44-4)
- 2-((5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-(2,4-difluorophenyl)acetamide (CAS 454458-56-1)
- 3-(Tert-butyl)-1-(5-(trifluoromethyl)pyridin-2-yl)indeno[1,2-c]pyrazol-4(1H)-one (CAS 1024537-54-9)
- 4-(4-(Pyridin-2-yl)pyrimidin-2-yl)phenyl 4-fluorobenzoate (CAS 477857-38-8)
- 6-(4-Benzyl-1-piperazinyl)-3-pyridinylamine (CAS 381706-46-3)
- 2-Methyl-5-(thiomorpholine-4-carbonyl)phenol (CAS 1042634-32-1)
- 1-(1H-imidazol-2-yl)-2-azabicyclo[2.1.1]hexane;dihydrochloride (CAS 2044744-70-7)
- 1-Isopropyl-5-oxopyrrolidine-3-carbonyl chloride (CAS 1181455-29-7)
- ethyl 5-(hydroxymethyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 856102-45-9)
- Dihydroactinidiolide (CAS 17092-92-1)
- 2-Amino-4-phosphonobenzenesulfonic acid (CAS 61433-33-8)
- 2-(2-Cyclohexylethoxy)-4-nitroaniline (CAS 928202-27-1)
- 3-((3-Hydroxybutyl)amino)thietane 1,1-dioxide (CAS 1864388-08-8)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com