Tert-butyl 4-(4-amino-2-fluorophenoxy)piperidine-1-carboxylate CAS 250372-00-0
| CAS No. | 250372-00-0 |
| Molecular Formula | C16H23FN2O3 |
| Molecular Weight | 310.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tert-butyl 4-(4-amino-2-fluorophenoxy)piperidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tert-butyl 4-(4-amino-2-fluorophenoxy)piperidine-1-carboxylate (CAS 250372-00-0), molecular formula C16H23FN2O3 and molecular weight 310.36 g/mol, is a CATO reference standard with documented purity and traceability.
Tert-butyl 4-(4-amino-2-fluorophenoxy)piperidine-1-carboxylate (C16H23FN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H23FN2O3 |
| Molecular Weight | 310.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-(2-(Dimethylamino)-2-(thiophen-3-yl)ethyl)-2,6-difluorobenzamide (CAS 946373-38-2)
- H-Arg-His-NH? (CAS 244765-93-3)
- N-(2-(Dimethylamino)-2-(thiophen-2-yl)ethyl)-2,6-difluorobenzamide (CAS 942000-02-4)
- (2E)-3-(1-benzyl-3-thien-2-yl-1H-pyrazol-4-yl)acrylic acid (CAS 1006463-87-1)
- Bis(4-chlorophenyl)(hydroxy)borane (CAS 89566-59-6)
- (R)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate (CAS 146553-06-2)
- Methyl 2-(1,3-thiazol-5-yl)acetate (CAS 16565-78-9)
- 3-Chloro-1-[4-(pyrimidin-2-yl)piperazin-1-yl]propan-1-one (CAS 137885-46-2)
- 2,6-Difluoro-N-hydroxybenzamide (CAS 125309-34-4)
- 3-Benzyl-3-azabicyclo[3.3.1]Nonane-1-carboxylic acid (CAS 1357354-26-7)
- 3-Chloro-2-isopropoxybenzaldehyde (CAS 894851-27-5)
- (3-(Bicyclo[1.1.1]Pentan-1-yl)phenyl)methanol (CAS 1823894-02-5)
- N-Cyclohexyl-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 1073354-73-0)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
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