2-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-oxoacetic acid CAS 250642-54-7
| CAS No. | 250642-54-7 |
| Molecular Formula | C9H6ClFO4 |
| Molecular Weight | 232.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-oxoacetic acid (CAS 250642-54-7), molecular formula C9H6ClFO4 and molecular weight 232.59 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-oxoacetic acid (C9H6ClFO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 232.59 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-oxoacetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6ClFO4 |
| Molecular Weight | 232.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
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- 3-Chloro-1-cyclopropyl-7-methyl-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile (CAS 1707568-81-7)
- 5-Bromo-2-chloro-4-fluorophenyl acetate (CAS 148254-36-8)
- 4-(2,3-Dimethoxyphenyl)-1-methylpyrrolidine-3-carboxylic acid (CAS 1706456-18-9)
- 2-(4-Bromo-3-chlorophenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244088-67-1)
- (2S,4R)-N-Fmoc-4-difluoromethoxy-Pro-OH (CAS 2382632-22-4)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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