5-Fluoro-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one CAS 250658-24-3
| CAS No. | 250658-24-3 |
| Molecular Formula | C5H5FN2OS |
| Molecular Weight | 160.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Fluoro-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 250658-24-3), a certified reference material (molecular formula C5H5FN2OS, MW 160.17 g/mol) for analytical method development and quality control.
The molecular framework of 5-Fluoro-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (C5H5FN2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Fluoro-1-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2OS |
| Molecular Weight | 160.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
- Methyl 3-Fluoro-2-thiophenecarboxylate (CAS 100421-52-1)
- 5-Fluoro-2-(methylthio)pyrimidin-4-ol (CAS 1480-92-8)
- 5-Fluoro-6-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one (CAS 148744-27-8)
- 2-Fluoro-2-(3-thienyl)acetic Acid (CAS 1514554-38-1)
- 6-Fluoro-2-methyl-2,3-dihydro-1H-indene-1-carboxylic acid (CAS 1544842-47-8)
- 3-fluoro-4-methylthiophene-2-carboxylic acid (CAS 1783331-06-5)
- 5-Fluoro-2-(methylsulfinyl)pyrimidine (CAS 1967005-91-9)
- 2-Fluoro-2-(thiophen-2-yl)acetic acid (CAS 94744-62-4)
Recommended Standards
- 5-Ethyl-5-(hydroxymethyl)-1,3-dioxan-2-one (CAS 38802-97-0)
- 5H-indeno[5,6-d][1,3]dioxole (CAS 267-28-7)
- 5-Ethoxy-5-hydroxy-1-methylimidazolidin-2-one (CAS 705282-68-4)
- 5-Methoxy-1H-inden-1-one (CAS 72913-59-8)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,2-difluoro-1-(piperazin-1-yl)ethan-1-one; trifluoroacetic acid (CAS 1823182-52-0)
- (-)-trans-5-Methyl-L-proline hydrochloride (CAS 38228-15-8)
- Tert-butyl 4-((3-(4-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)piperazine-1-carboxylate (CAS 1781241-47-1)
- Prasugrel Impurity 22 (CAS 204205-33-4)
- ethyl isocyanide DISCONTINUED (CAS 624-79-3)
- 4-Amino-1,2-dimethylpiperidine-4-carboxylic acid (CAS 1259055-68-9)
- Chroman-8-carbonyl Chloride (CAS 1034566-09-0)
- 3-Aminoquinoline-2-carbonitrile (CAS 1935579-44-4)
- (1S,2R)-2-(methoxymethyl)cyclobutan-1-amine (CAS 1932078-51-7)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
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