4-(4-Methylpiperazin-1-yl)-3-fluorobenzonitrile CAS 250683-77-3
| CAS No. | 250683-77-3 |
| Molecular Formula | C12H14FN3 |
| Molecular Weight | 219.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-(4-Methylpiperazin-1-yl)-3-fluorobenzonitrile (C12H14FN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 219.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 4-(4-Methylpiperazin-1-yl)-3-fluorobenzonitrile (CAS 250683-77-3), a certified reference material (molecular formula C12H14FN3, MW 219.26 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Methylpiperazin-1-yl)-3-fluorobenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14FN3 |
| Molecular Weight | 219.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methylpiperazin Standards
- 5-Methyl-6-(4-methylpiperazin-1-yl)nicotinaldehyde (CAS 1355174-52-5)
- 2-Methyl-6-(4-methylpiperazin-1-yl)nicotinaldehyde (CAS 1355192-41-4)
- 4-Methyl-6-(4-methylpiperazin-1-yl)nicotinaldehyde (CAS 1355193-12-2)
- 1-(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)ethanone (CAS 1377962-52-1)
- 4-(4-Methylpiperazin-1-yl)picolinimidamide (CAS 1343783-65-2)
- 3-(2-(4-Methylpiperazin-1-yl)ethyl)aniline (CAS 1018294-23-9)
- (1-benzyl-4-methylpiperazin-2-yl)methanamine (CAS 56904-13-3)
- (4-[(4-Methylpiperazin-1-yl)methyl]phenyl)methylamine (CAS 515162-20-6)
Recommended Standards
- 4-(4-Methyl-1,3-thiazol-2-yl)benzoic acid (CAS 933709-38-7)
- 4-(M-tolyl)thiazole-2-carboxylic acid (CAS 952959-36-3)
- 4-(4-Methoxyphenyl)thiazole-2-carbaldehyde (CAS 383144-12-5)
- 4-Amino-N-(2-thiazolyl)benzamide (CAS 247225-81-6)
- 6-Bromothiazolo[4,5-b]pyrazin-2-amine (CAS 112342-72-0)
- (R,S)-4-Fmoc-3-carboxymethyl-piperazin-2-one (CAS 1029630-75-8)
- (-)-Isoborneolacetic acid 2-((1R,2S,3R,4R)-3-hydroxy-1,4,7,7-tetramethylbicyclo[2.2.1]heptan-2-yl)acetic acid 81925-04-4 (CAS 81925-04-4)
- 3-[(1-methyl-1h-imidazol-2-yl)sulfanyl]propanoic acid (CAS 919467-05-3)
- 3-[(tert-butoxy)carbonyl]-1,3-thiazolidine-2-carboxylic acid (CAS 141783-63-3)
- (S)-2-Aminopentanoic acid hydrochloride (CAS 27493-23-8)
- 1-[4-(3-oxocyclobutyl)phenyl]hexahydropyrimidine-2,4-dione (CAS 2797942-83-5)
- (2S)-2-amino-2-cyclopropyl-ethanol;hydrochloride (CAS 1623432-63-2)
- Nintedanib Impurity 113 (CAS CATO-C4X-1814113)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com