5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1H-1,2,4-triazol-3-amine CAS 250714-16-0
| CAS No. | 250714-16-0 |
| Molecular Formula | C8H5ClF3N5S |
| Molecular Weight | 295.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1H-1,2,4-triazol-3-amine (C8H5ClF3N5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1H-1,2,4-triazol-3-amine (CAS 250714-16-0), molecular formula C8H5ClF3N5S and molecular weight 295.67 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1H-1,2,4-triazol-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3N5S |
| Molecular Weight | 295.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 5-[[3-Chloro-5-(trifluoromethyl)-2-pyridyl]-methyl]-1,3,4-oxadiazole-2-thiol (CAS 1987078-26-1)
- Methyl 5-chloro-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate (CAS 648859-81-8)
- 3-((4-Chloro-3-nitro-1h-pyrazol-1-yl)methyl)benzohydrazide (CAS 1001757-43-2)
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- Ethyl 5-chloro-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate (CAS 110821-37-9)
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Recommended Standards
- 3-(Trifluoromethyl)quinoline-7-sulfonyl chloride (CAS 1956332-63-0)
- 2-Nitro-4-(trifluoromethyl)benzenesulfonyl chloride 2-nitro-4-(trifluoromethyl)benzenesulphonyl chloride 2-nitro-4-(trifluoromethyl)benzenesulfonylchloride 2-nitro-4(trifluoromethyl)benzene sulfonyl chloride 837-95-6 (CAS 837-95-6)
- Dabrafenib Impurity 25 (CAS 1353575-68-4)
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[(Z)-N'-hydroxycarbamimidoyl]acetamide (CAS 219528-44-6)
- 2-Ethoxy-2-oxoethyl ethyl malonate (CAS 100074-94-0)
- Methyldiazinol - API Standards (CAS 2429-17-6)
- (4S,4′S)-2,2′-(5,5′-Dimethoxy[1,1′-biphenyl]-2,2′-diyl)bis[4,5-dihydro-4-phenyloxazole] (CAS 944133-17-9)
- Folate-PEG1-mal (CAS 2743004-48-8)
- Cefamandole Impurity 20 (CAS CATO-C4X-122120)
- Sodium (S)-pyrrolidine-2-carboxylate (CAS 15383-56-9)
- (4R,6S)-4-Phenyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 88980-08-9)
- 4-Bromo-3-nitrobenzotrifluoride (CAS 349-03-1)
- FMoc-d-his(trt)-opfp (CAS 1423017-93-9)
- Peptide Impurity 26 (CAS 1350456-66-4)
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