2-(4-Chlorophenoxy)-2,2-difluoro-N-(2-fluorophenyl)acetamide CAS 250714-69-3
| CAS No. | 250714-69-3 |
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C14H9ClF3NO2, 2-(4-Chlorophenoxy)-2,2-difluoro-N-(2-fluorophenyl)acetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 315.67 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-(4-Chlorophenoxy)-2,2-difluoro-N-(2-fluorophenyl)acetamide (CAS 250714-69-3), a certified reference material (molecular formula C14H9ClF3NO2, MW 315.67 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorophenoxy)-2,2-difluoro-N-(2-fluorophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
- 2-(4-Chlorophenoxy)-2,2-difluoro-N-(4-fluorophenyl)acetamide (CAS 250714-55-7)
- 5-(4-(4-Chlorophenoxy)phenyl)isoxazole-3-carboxylic acid (CAS 925001-05-4)
- N-[2-(2-Chlorophenoxy)ethyl]-3-(trifluoromethyl)aniline (CAS 1040685-01-5)
- 2-(4-Chlorophenoxy)-N-(pyrazolo[1,5-a]pyridin-3-ylmethyl)acetamide (CAS 1396557-92-8)
- 1-[2-(2-chlorophenoxy)ethyl]-1h-indole-2-carboxylic acid (CAS 1423032-59-0)
- 1-[2-(2-chlorophenoxy)ethyl]-1h-indole-3-carboxylic acid (CAS 892255-06-0)
- 2-(4-Chlorophenoxy)-2-(4-methoxyphenoxy)cyclopropanecarbonitrile (CAS 651306-64-8)
- 3-(2-(4-Chlorophenoxy)phenyl)-1-methylpyrrolidine-2,4-dione (CAS 912356-07-1)
Recommended Standards
- 1-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)ethan-1-one (CAS 217186-15-7)
- 1-(3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)ethan-1-one (CAS 478065-94-0)
- Methyl 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]benzenecarboxylate (CAS 885949-65-5)
- 1-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)ethan-1-one (CAS 478065-93-9)
- 7-Bromospiro[indoline-3,4'-piperidin]-2-one hydrochloride (CAS 1707602-26-3)
- (R)-4-(cyclopropylamino)-2-((3-nitroso-1,2,3,4,4a,5-hexahydrobenzo[b]pyrazino[1,2-d][1,4]oxazin-8-yl)amino)pyrimidine-5-carboxamide (CAS CATO-C3D-262543)
- 1-Acetyl-3-azetidinecarboxylic Acid (CAS 97628-91-6)
- N-benzyl-2-bromo-5-(trifluoromethoxy)benzenesulfonamide (CAS 951885-49-7)
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- 4,6-Dichloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 4228-88-0)
- 2-[(tert-butoxy)methyl]benzoic acid (CAS 857005-12-0)
- 5-Ethyl-1-methoxy-5,10-dihydrophenazine ethyl sulfate (CAS 133395-54-7)
- 1,3-Diphenyl-1H-pyrazol-4-ol (CAS 1202029-92-2)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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