2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine CAS 251096-56-7
| CAS No. | 251096-56-7 |
| Molecular Formula | C17H9Cl2F3N6S |
| Molecular Weight | 457.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (CAS 251096-56-7), molecular formula C17H9Cl2F3N6S and molecular weight 457.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine (C17H9Cl2F3N6S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-6-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H9Cl2F3N6S |
| Molecular Weight | 457.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 8-Chloro-5-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4(5H)-one (CAS 303986-22-3)
- (E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)amino 4-chlorobenzoate (CAS 306976-45-4)
- Ethyl 5-(((4-chloro-N-(4-chlorophenyl)phenyl)sulfonamido)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 306978-11-0)
- 3-Chloro-N-(2,2,2-trichloro-1-((4-sulfamoylphenyl)amino)ethyl)benzamide (CAS 302954-32-1)
- 4-Chloro-N-((5-((4-chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide (CAS 338421-95-7)
- N-[5-[2-(5-Chloro-2-methoxy-anilino)thiazol-4-yl]-4-methyl-thiazol-2-yl]benzamide (CAS 421580-53-2)
- 2-((7-Chloro-3-(furan-2-ylmethyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(1-cyanocyclohexyl)acetamide (CAS 852411-17-7)
- 4-Chloro-2-(4-(N,N-diethylsulfamoyl)phenyl)quinoline-6-sulfonyl fluoride (CAS 31242-12-3)
Recommended Standards
- 1-Chlorotriacontane (CAS 62016-82-4)
- N-(2,4-dichloro-5-methoxyphenyl)-3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxamide (CAS 339015-56-4)
- 4-Bromo-N-{3-[5-(trifluoromethyl)pyridin-2-yl]phenyl}benzene-1-sulfonamide (CAS 1092346-17-2)
- Methyl 5-(1-(4-acetylphenyl)-1H-1,2,3-triazol-4-yl)-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate (CAS 439110-54-0)
- (4,5-Dichloropyridin-2-yl)methanol (CAS 154780-03-7)
- 1-(Difluoromethyl)-4-methoxynaphthalene (CAS 867377-17-1)
- 4-((4-(Aminomethyl)pyridin-2-yl)oxy)cyclohexan-1-one oxalate (CAS 1820650-61-0)
- 1-(2-Morpholino-2-oxoethyl)-1H-indole-3-carbaldehyde (CAS 335207-46-0)
- 2-[(2-fluorophenyl)methyl]-1,3-thiazole-4-carboxylic acid (CAS 1216196-70-1)
- Clopidogrel Impurity 32 (CAS 1258938-54-3)
- 5-Amino-3-(methylamino)pyrazine-2-carboxamide (CAS 704-46-1)
- 1-(2-Chloro-5-(difluoromethoxy)phenyl)propan-1-one (CAS 1261478-73-2)
- Ethyl 6-bromo-5-fluoronicotinate (CAS 1214337-76-4)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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