((2-Chlorophenyl)sulfonyl)leucine CAS 251097-66-2
| CAS No. | 251097-66-2 |
| Molecular Formula | C12H16ClNO4S |
| Molecular Weight | 305.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), ((2-Chlorophenyl)sulfonyl)leucine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies ((2-Chlorophenyl)sulfonyl)leucine (CAS 251097-66-2), a certified reference material (molecular formula C12H16ClNO4S, MW 305.78 g/mol) for analytical method development and quality control.
The molecular framework of ((2-Chlorophenyl)sulfonyl)leucine (C12H16ClNO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H16ClNO4S |
| Molecular Weight | 305.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 3-(6-(4-Chlorophenyl)imidazo[2,1-b]thiazol-3-yl)propanamide (CAS 1040647-27-5)
- N-[(3-Chlorophenyl)sulfonyl]-L-leucine (CAS 1132787-68-8)
- ((4-Chlorophenyl)sulfonyl)leucine (CAS 169187-00-2)
- Methyl 4-[(4-chlorophenyl)(methylsulfonyl)amino]butanoate (CAS 1858241-99-2)
- Methyl 4-[(3-chlorophenyl)(methylsulfonyl)amino]butanoate (CAS 1858251-33-8)
- ((4-Chlorophenyl)sulfonyl)-l-leucine (CAS 68305-77-1)
- (E)-2-((4-chlorophenyl)thio)-N'-(pyridin-3-ylmethylene)acetohydrazide (CAS 329699-47-0)
- {[(2E)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]sulfamoyl}dimethylamine (CAS 672951-79-0)
Recommended Standards
- (S)-2-((tert-butoxycarbonyl)amino)-3-(5-chlorothiophen-2-yl)propanoic acid (CAS 190319-94-9)
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- (5-Chloro-2-(methylthio)pyrimidin-4-yl)(indolin-1-yl)methanone (CAS 898647-03-5)
- (E)-({6-chloroimidazo[2,1-b][1,3]thiazol-5-yl}methylidene)[(2-methoxyphenyl)methyl]amine (CAS 338396-10-4)
- 2-Bromo-N-(2-methyl-2-morpholinopropyl)acetamide hydrobromide (CAS 1384428-86-7)
- n-[(4-aminophenyl)methyl]methanesulfonamide (CAS 81880-95-7)
- 6-Methoxy-2-(4-methoxyphenyl)-3-(m-tolyloxy)benzo[b]thiophene 1-oxide (CAS 477762-68-8)
- 4-bromo-1-cyclopentyl-1H-pyrazol-3-amine (CAS 1006470-56-9)
- Methyl 2-(2,4-dioxo-2H-benzo[d][1,3]oxazin-1(4H)-yl)acetate (CAS 96222-36-5)
- 3-(3,3-Dimethylbutyl)piperidin-3-ol (CAS 1496402-12-0)
- 5-Oxo-5-{3-oxo-2-[2-oxo-2-(phenethyloxy)ethyl]-1-piperazinyl}pentanoic acid (CAS 1042701-26-7)
- 1-Biphenyl-2-yl-N-methylmethylamine (CAS 13737-31-0)
- Z-Ala-Gly-Gly-OH (CAS 21929-69-1)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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