2-(Dicyclohexylphosphino)-2'-methylbiphenyl CAS 251320-86-2
| CAS No. | 251320-86-2 |
| Molecular Formula | C25H33P |
| Molecular Weight | 364.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Dicyclohexylphosphino)-2'-methylbiphenyl (CAS 251320-86-2), molecular formula C25H33P and molecular weight 364.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Dicyclohexylphosphino)-2'-methylbiphenyl (C25H33P) is characterized by organophosphorus functionality, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Dicyclohexylphosphino)-2'-methylbiphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H33P |
| Molecular Weight | 364.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Dicyclohexylphosphino Standards
- 2-(Dicyclohexylphosphino)biphenyl 247940-06-3 (2-BIPHENYL)DICYCLOHEXYLPHOSPHINE;(2-BIPHENYLYL)DICYCLOHEXYLPHOSPHINE;2-(DICYCLOHEXYLPHOSPHINO)BIPHENYL;2-(DICYLOHEXYLPHOSPHINO)BIPHENYL;BIPHENYL-2-YLDICYCLOHEXYLPHOSPHINE;CYCLOHEXYL JOHNPHOS;DICYCLOHEXYL(2-PHENYLPHENYL)PHOSPHANE;PHOSPHINE, [1,1'-BIPHENYL]-2-YLDICYCLOHEXYL-;[1,1'-BIPHENYL]-2-YLDICYCLOHEXYLPHOSPHINE GC10123 (CAS 247940-06-3)
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- 2-(Dicyclohexylphosphino)-2'-methoxy-1,1'-biphenyl (CAS 255835-82-6)
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- N-(2-(Dicyclohexylphosphino)benzylidene)cyclohexanamine (CAS 820964-95-2)
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Recommended Standards
- 2-(Benzylamino)-4,4-dimethyl-6-oxo-N-phenylcyclohex-1-ene-1-carbothioamide (CAS 41609-06-7)
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- Cd 2314 (CAS 170355-37-0)
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- 3-(5-amino-1-oxo-isoindolin-2-yl)-1-methyl-piperidine-2,6-dione (CAS 2768326-37-8)
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- (2S,3S,4S,5R,6S)-6-(2-aminophenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid (CAS 15959-03-2)
- 2-Phenylimidazo[1,2-a]pyridine-6-carboxylic acid (CAS 1027-01-6)
- Benzocaine EP Impurity A (CAS 623-04-1)
- 3-(3-Aminophenyl)-4,5-dihydroisoxazole-5-carbonitrile (CAS 1173460-41-7)
- 3-Bromo-N-methyl-1-propanamine Hydrobromide (CAS 60035-88-3)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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