Vonoprazan Impurity 160 CAS 2514735-12-5
| CAS No. | 2514735-12-5 |
| Molecular Formula | C28H24F2N4O2S |
| Molecular Weight | 518.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Vonoprazan Impurity 160 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Vonoprazan Impurity 160 (CAS 2514735-12-5, C28H24F2N4O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C28H24F2N4O2S, Vonoprazan Impurity 160 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 518.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C28H24F2N4O2S |
| Molecular Weight | 518.58 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 220 (CAS CATO-C4X-1020220)
- Vonoprazan Impurity 230 (CAS CATO-C4X-1020230)
- Vonoprazan Impurity 166 (CAS CATO-C4X-1020166)
- Vonoprazan Impurity 175 (CAS CATO-C4X-1020175)
- Vonoprazan Impurity 55 (CAS 2514957-29-8)
- Vonoprazan Impurity 295 (CAS CATO-C4X-1020295)
- Vonoprazan Impurity 266 (CAS CATO-C4X-1020266)
- Vonoprazan Impurity 234 (CAS CATO-C4X-1020234)
Recommended Standards
- Perfluorooctanesulfonyl Chloride (CAS 423-60-9)
- Ethyl 5-(4-acetoxyphenyl)-2-(4-(allyloxy)benzylidene)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 324568-15-2)
- Ethyl 2-({7-hydroxy-3-[(4-methoxyphenyl)carbamoyl]-2H-chromen-2-ylidene}amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 330663-43-9)
- Meropenem Impurity 13 (CAS CATO-C4X-130913)
- Spectinomycin EP Impurity A Dihydrochloride (CAS 52049-70-4)
- Sugammadex Impurity 67 (CAS CATO-C4X-190677)
- Beclometasone Dipropionate Monohydrate EP Impurity D (CAS 52092-14-5)
- N-(Furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)thiophene-3-carboxamide (CAS 1421494-18-9)
- 3-(Hydroxymethyl)thiomorpholine 1,1-dioxide (CAS 1784079-68-0)
- 4-(2,2,3,3-Tetrafluoropropoxy)aniline hydrochloride (CAS 109230-81-1)
- Ethyl 4-(2-(tert-butoxy)-2-oxoethylidene)cyclohexane-1-carboxylate (CAS 218779-74-9)
- Esmolol Impurity 49 (CAS CATO-C4X-189149)
- 2-Benzoyl-3-methylnaphthalene-1,4-dione (CAS 17579-92-9)
- D-Ala28-Tirzepatide (CAS CATO-CPTD788906)
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