Apixaban Impurity 109 CAS 2514951-00-7
| CAS No. | 2514951-00-7 |
| Molecular Formula | C27H26N4O5 |
| Molecular Weight | 486.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apixaban Impurity 109 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Apixaban Impurity 109 (CAS 2514951-00-7) is a certified pharmaceutical impurity reference standard with the molecular formula C27H26N4O5 and a molecular weight of 486.52 g/mol.
Structurally, Apixaban Impurity 109 (C27H26N4O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 486.52 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C27H26N4O5 |
| Molecular Weight | 486.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban USP Related Compound D (CAS 1351611-14-7)
- Apixaban Impurity 138 (CAS CATO-C4X-1088138)
- Apixaban Impurity 153 (CAS CATO-C4X-1088153)
- Apixaban Impurity 9 (CAS 503614-91-3)
- Apixaban Impurity 32 (CAS CATO-C4X-108832)
- Apixaban Impurity 75 (CAS CATO-C4X-108875)
- Apixaban Impurity 173 (CAS CATO-C4X-1088173)
- Apixaban Impurity 150 (CAS CATO-C4X-1088150)
Recommended Standards
- Tigecycline Impurity 29 (CAS 488820-34-4)
- Oxcarbazepine EP Impurity M (CAS 2642430-32-6)
- N-(4-Cyanophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,9-tetrahydro-1H-purin-8-yl)phenoxy)acetamide (CAS 264622-58-4)
- Clindamycin Phosphas EP Impurity F (CAS 27480-30-4)
- Prasugrel Impurity 35 (CAS CATO-C4X-108635)
- Ipratropium Impurity 27 (CAS CATO-C4X-166527)
- Lidocaine Impurity 57 (CAS 102878-74-0)
- TNP-470 (CAS 129298-91-5)
- 3-Fluoro-2-methyl-N-(pentan-3-yl)aniline (CAS 1249672-94-3)
- 4-(2-Fluorobenzamido)benzoic acid (CAS 300713-78-4)
- 1-(Methylsulfonyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidine (CAS 1428329-80-9)
- 7-Chloro-3-(2-methylpropyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 731827-21-7)
- ML 349 (CAS 890819-86-0)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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