25189-55-3 CHEBI:53234 N-(1-Methylethyl)-2-propenamide homopolymer PNIPAAm PNIPAM Poly-N-isopropylacrylamide poly(N-isopropyl-acrylamide) poly(N-isopropylacrylamide) poly(N-isopropylacrylamide) macromolecule poly(NIPAM) poly[1-(isopropylcarbamoyl)ethylene] CAS 25189-55-3

Purity 97%+In StockPharmaceutical Standards
CAS No.25189-55-3
Molecular FormulaC6H11NO
Molecular Weight113.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

25189-55-3
CHEBI:53234
N-(1-Methylethyl)-2-propenamide homopolymer
PNIPAAm
PNIPAM
Poly-N-isopropylacrylamide
poly(N-isopropyl-acrylamide)
poly(N-isopropylacrylamide)
poly(N-isopropylacrylamide) macromolecule
poly(NIPAM)
poly[1-(isopropylcarbamoyl)ethylene] CAS 25189-55-3 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

25189-55-3 CHEBI:53234 N-(1-Methylethyl)-2-propenamide homopolymer PNIPAAm PNIPAM Poly-N-isopropylacrylamide poly(N-isopropyl-acrylamide) poly(N-isopropylacrylamide) poly(N-isopropylacrylamide) macromolecule poly(NIPAM) poly[1-(isopropylcarbamoyl)ethylene] (CAS 25189-55-3) is a high-purity analytical reference standard with the molecular formula C6H11NO and a molecular weight of 113.16 g/mol.

Owing to an amide group, a hydroxyl group, an ether linkage, 25189-55-3 CHEBI:53234 N-(1-Methylethyl)-2-propenamide homopolymer PNIPAAm PNIPAM Poly-N-isopropylacrylamide poly(N-isopropyl-acrylamide) poly(N-isopropylacrylamide) poly(N-isopropylacrylamide) macromolecule poly(NIPAM) poly[1-(isopropylcarbamoyl)ethylene] is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 113.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC6H11NO
Molecular Weight113.16 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1964
Nitrogen Atoms1

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