Isoniazid Impurity 1 CAS 25197-87-9
| CAS No. | 25197-87-9 |
| Molecular Formula | C18H27N3O11 |
| Molecular Weight | 461.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isoniazid Impurity 1.
Isoniazid Impurity 1 (CAS 25197-87-9) is a certified pharmaceutical impurity reference standard with the molecular formula C18H27N3O11 and a molecular weight of 461.42 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Isoniazid Impurity 1 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 461.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Isoniazid Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H27N3O11 |
| Molecular Weight | 461.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 3 |
Related Isoniazid Standards
Recommended Standards
- 4-Azidophlorizin (CAS 79541-46-1)
- 1-(2,4-Difluorophenyl)-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-17-6)
- β-D-tetraacetylgalactopyranoside-PEG1-N3 (CAS 153252-36-9)
- 1-(2,4-Difluorophenyl)-7-(4-ethylpiperazin-1-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 182869-19-8)
- Dronedarone Impurity 41 (CAS 94107-99-0)
- Crisaborole Impurity 16 (CAS 906673-43-6)
- Norepinephrine Impurity 24 (CAS 62932-90-5)
- N-(3-(trifluoromethyl)phenyl)benzofuran-2-carboxamide (CAS 302583-11-5)
- 3-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-(4-phenylpiperazin-1-yl)-1,2,4,5-tetrazine (CAS 318239-47-3)
- 2-(6-Bromo-2-oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acid (CAS 653599-23-6)
- 2-(2-Bromo-6-nitrophenyl)acetic Acid (CAS 37777-74-5)
- 1-(2-Chloropyrimidin-4-yl)piperidin-4-ol (CAS 94222-07-8)
- 4-(5-Fluoropyridin-2-yl)morpholine (CAS 1287217-51-9)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com