非索非那定杂质1 CAS 252022-32-5
| CAS No. | 252022-32-5 |
| Molecular Formula | C15H21ClO3 |
| Molecular Weight | 284.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 非索非那定杂质1 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 非索非那定杂质1 (CAS 252022-32-5), a pharmacopoeial impurity reference standard (molecular formula C15H21ClO3, MW 284.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, 非索非那定杂质1 (C15H21ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 284.78 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures 非索非那定杂质1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H21ClO3 |
| Molecular Weight | 284.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Recommended Standards
- 898786-81-7 7-Chloro-1-(3,4-dimethoxyphenyl)heptan-1-one DTXSID30645201 (CAS 898786-81-7)
- Metoclopramide impurity 53 (CAS CATO-C4X-141553)
- Tert-butyl (2-((4-chlorobenzyl)amino)ethyl)carbamate (CAS 335059-94-4)
- Hexachlorobenzene (CAS 118-74-1)
- tert-Butyl ((2S,4R,5S)-5-amino-4-hydroxy-1,6-diphenylhexan-2-yl)carbamate (Ritonavir Impurity ) (CAS 1414933-83-7)
- Doxapram impurity 41 (CAS 2735956-96-2)
- Camphor EP Impurity H (CAS CATO-C4X-211413)
- 2-Fluoro-N-(5-((2-(hydroxyamino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide (CAS 878065-25-9)
- 2-Methoxyquinoline-8-carboxylic acid (CAS 1824140-76-2)
- 2-(4-(Adamantan-1-yl)phenoxy)-1-(4-methylpiperazin-1-yl)ethanone (CAS 1429054-28-3)
- 4-Ethyl-2-isopropoxyphenol (CAS 1243370-36-6)
- (8AR,9R,10R,11aR,Z)-10-hydroxy-9-((S,E)-3-hydroxyoct-1-en-1-yl)-4,5,8,8a,9,10,11,11a-octahydrocyclopenta[b]oxecin-2(3H)-one (CAS 55314-48-2)
- Hexanedioic acid, polymer with 1,2-propanediol and 2,2,4-trimethyl-1,3-pentanediol, 2-ethylhexyl ester (CAS 150632-05-6)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com