Methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate CAS 252025-50-6
| CAS No. | 252025-50-6 |
| Molecular Formula | C16H12Cl2N2O2 |
| Molecular Weight | 335.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 335.18 g/mol gives Methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate (CAS 252025-50-6) is a high-purity analytical reference standard with the molecular formula C16H12Cl2N2O2 and a molecular weight of 335.18 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2N2O2 |
| Molecular Weight | 335.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 1-(2,4-Dichlorobenzyl)-2-methyl-1H-benzo[d]imidazole-6-carboxylic acid (CAS 193010-16-1)
- 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carbohydrazide (CAS 252025-52-8)
- 3-(2,6-Dichlorobenzyl)-2-methyl-1-(4H-1,2,4-triazol-4-yl)pyridin-4(1H)-one (CAS 923200-01-5)
- 3-(3,4-Dichlorobenzyl)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one (CAS 866043-33-6)
- 2-((2,4-Dichlorobenzyl)thio)-1-phenyl-1H-imidazole (CAS 478046-21-8)
- 2,4-Dichlorobenzyl Alcohol EP Impurity G (CAS 207974-13-8)
- 5-(((2,6-Dichlorobenzyl)thio)methyl)-4-ethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 344269-70-1)
- 3-((2,4-Dichlorobenzyl)oxy)benzo[b]thiophene-2-carbonitrile (CAS 303985-57-1)
Recommended Standards
- 8-Fluoro-4-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 2370912-04-0)
- N-(1,1-Dioxidotetrahydrothiophen-3-yl)dodecanamide (CAS 24373-83-9)
- 7-((3-Chlorobenzyl)oxy)-4-(chloromethyl)-2H-chromen-2-one (CAS 911290-21-6)
- Clopidogrel Impurity 58 (CAS CATO-C4X-102958)
- 2-(5-amino-1,3,4-thiadiazol-2-yl)propan-2-ol (CAS 933911-74-1)
- N-(2-(1H-imidazol-1-yl)ethyl)tetrahydro-2H-thiopyran-4-amine dihydrochloride (CAS 1909319-20-5)
- (4S)-3-[4-[2-(4-Fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone (CAS 953805-20-4)
- 2-Ethoxy-5-nitropyridine (CAS 31594-45-3)
- Methyl 4-[(5-methyl-1H-tetrazol-1-yl)methyl]benzoate (CAS 1706459-79-1)
- (E)-N'-(3,5-Dimethylphenyl)-N-{2-[N-(3-fluoropropyl)4-nitrobenzenesulfonamido]ethyl}-N-methylethanimidamide (CAS 866132-99-2)
- 3-Methyl-7-nitrobenzofuran (CAS 164075-27-8)
- N-(4-Amino-5-(4-chlorophenyl)-6-ethylpyrimidin-2-yl)acetamide (CAS 74124-11-1)
- N-benzyl-1-(1,2-dimethyl-1H-imidazol-5-yl)methanamine (CAS 2012647-56-0)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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