4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine CAS 252198-68-8
| CAS No. | 252198-68-8 |
| Molecular Formula | C14H9Cl2N3S |
| Molecular Weight | 322.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine (CAS 252198-68-8), molecular formula C14H9Cl2N3S and molecular weight 322.21 g/mol, is a CATO reference standard with documented purity and traceability.
4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine (C14H9Cl2N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(3,4-Dichlorophenyl)-5-(pyridin-4-yl)thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9Cl2N3S |
| Molecular Weight | 322.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- (2Z)-1-(3,4-Dichlorophenyl)-3-(dimethylamino)-2-methanesulfonylprop-2-en-1-one (CAS 344275-67-8)
- (3Z)-3-{[(2,5-dichlorophenyl)amino]methylidene}-1,3-dihydro-2-benzothiophen-1-one (CAS 339114-99-7)
- 3-(((3,4-Dichlorophenyl)imino)methyl)benzo[c]thiophen-1-ol (CAS 339114-93-1)
- 5-(2,4-Dichlorophenyl)-4-phenyl-4h-1,2,4-triazole-3-thiol (CAS 92151-02-5)
- N-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]pyridin-3-amine (CAS 497060-07-8)
- (2,4-Dichlorophenyl)(3-methyl-2,3-dihydro-4H-benzo[b][1,4]oxazin-4-yl)methanone (CAS 478043-15-1)
- (3E)-3-{[(2,6-dichlorophenyl)methoxy]imino}-1-phenylpropan-1-one (CAS 338976-81-1)
- 2-[3-[2-(2,4-dichlorophenyl)hydrazono]-1-(dimethylamino)propylidene]malononitrile (CAS 339103-09-2)
Recommended Standards
- 2-[(2,4-dichlorobenzoyl)amino]-4-(methylthio)butanoic acid (CAS 65054-77-5)
- Bis(4-chlorophenyl)-4h-1,2,4-triazole-3-thiol (CAS 31405-28-4)
- 2,5-Dichloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-methylbenzamide (CAS 898425-57-5)
- 2,3-Dichloro-N-cyclopropyl-4-(ethylsulfonyl)benzamide (CAS 338391-82-5)
- 3-(4-Bromo-2-chlorophenoxy)propane-1-sulfonyl chloride (CAS 1407337-40-9)
- 3-Methyl-4H-pyrimido[2,1-c][1,2,4]triazine (CAS 744147-53-3)
- Pyrimidine<I>N</I>-oxide (CAS 17043-94-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-methyl-1H-pyrazol-1-yl)furan-2-yl)boronate (CAS 2223031-76-1)
- Ethyl 1-(3,4-dimethylphenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1159691-86-7)
- 1-[5-(4-Chlorophenyl)-4-methyl-1,1-dioxido-isothiazol-3-yl]piperidin-4-amine hydrochloride (CAS 1417567-73-7)
- (4-Amino-3-methylthieno[2,3-c]isothiazol-5-yl)(p-tolyl)methanone (CAS 339017-23-1)
- 2-Fluoro-3-(pyridin-4-yl)-5-(trifluoromethyl)pyridine (CAS 1214372-68-5)
- 4-Hydrazinyl-N-phenyl-6-(piperidin-1-yl)-1,3,5-triazin-2-amine (CAS 302955-73-3)
- Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 330456-24-1)
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