Avibactam Impurity 74 CAS 2523-37-7
| CAS No. | 2523-37-7 |
| Molecular Formula | C14H12 |
| Molecular Weight | 180.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 180.25 g/mol gives Avibactam Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Avibactam Impurity 74 (CAS 2523-37-7, C14H12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Avibactam Impurity 74 (C14H12) contains a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12 |
| Molecular Weight | 180.25 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Avibactam Standards
- Avibactam Impurity 12 (CAS 1383814-64-9)
- Avibactam Impurity 60 (CAS CATO-C4X-134860)
- Avibactam Impurity 59 (CAS CATO-C4X-134859)
- Avibactam impurity 100 (CAS CATO-C4X-1348100)
- Avibactam Impurity 43 (CAS 65275-12-9)
- Avibactam Impurity 64 (CAS CATO-C4X-134864)
- Avibactam Impurity 61 (CAS CATO-C4X-134861)
- Avibactam Impurity 130 (CAS CATO-C4X-1348130)
Recommended Standards
- Naphthylterbinafine-nitrosamine (CAS CATO-C4X-133826)
- Mianserin Impurity 80 (CAS 1260761-23-6)
- CAS 62-48-6 (CAS 62-48-6)
- Itopride Impurity 29 (CAS CATO-C4X-137729)
- Melphalan Impurity 37 (CAS CATO-C4X-198837)
- Crisaborole impurity 160 (CAS CATO-C4X-2021160)
- Loratadine Impurity 46 (CAS CATO-C4X-142646)
- N1,N1-Diethyl-N3-phenylpropane-1,3-diamine hydrochloride (CAS 58050-41-2)
- Methyl (R)-2-aminohexanoate hydrochloride (CAS 60687-33-4)
- 3-(4-Chlorophenyl)-5-methylisoxazole-4-carbaldehyde (CAS 127426-59-9)
- Manganese(ii)2-ethylhexanoate (CAS 13434-24-7)
- Tryptophan EP Impurity F HCl (CAS 145545-23-9（free base）)
- A 769662 (CAS 844499-71-4)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
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