(e)-3-(1-((2r,4s,5r)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-n-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide CAS 252337-58-9
| CAS No. | 252337-58-9 |
| Molecular Formula | C20H27F3N4O7 |
| Molecular Weight | 492.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, (e)-3-(1-((2r,4s,5r)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-n-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide (C20H27F3N4O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 492.45 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies (e)-3-(1-((2r,4s,5r)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-n-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide (CAS 252337-58-9), a certified reference material (molecular formula C20H27F3N4O7, MW 492.45 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (e)-3-(1-((2r,4s,5r)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-n-(6-(2,2,2-trifluoroacetamido)hexyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H27F3N4O7 |
| Molecular Weight | 492.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- 4-[(R)-3-[4-Cyano-3-(trifluoromethyl)phenyl]-4-oxo-2-thioxo-7-oxa-1,3-diazaspiro[4.4]non-1-yl]-2-fluoro-N-methylbenzamide (CAS 1351185-54-0)
- N-(2-Bromo-4-methylphenyl)-2-((3-ethyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 618879-71-3)
- Ethyl 1-tosyl-7-(((trifluoromethyl)sulfonyl)oxy)-1H-pyrrolo[3,2-c]pyridine-6-carboxylate (CAS 1207175-44-7)
- Relugolix Impurity 86 (CAS CATO-C4X-242986)
- 3,5-Bis(trifluoromethyl)benzylamine 3,5-bis(trifluoromethyl)benzyl amine 3, 5-bis(trifluoromethyl)benzylamine 3,5-di(trifluoromethyl)benzylamine 3,5-bis-trifluoromethyl-benzylamine 3,5-ditrifluoromethylbenzylamine 3,5-bis(trifluoromethyl) benzylamine 3,5-Bis(trifluoromethyl)benzenemethanamine [3,5-Bis(trifluoromethyl)phenyl]methanamine [[3,5-Bis(trifluoromethyl)phenyl]methyl]amine 85068-29-7 (CAS 85068-29-7)
- 5-Butyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one (CAS 168686-47-3)
- 4-(((4-Bromophenyl)sulfonyl)methyl)benzoic acid (CAS 110046-40-7)
- Amitraz-d6 (CAS CATO-CCPD103164)
- 2-(5,6,7-trifluoro-1H-indol-3-yl)ethan-1-amine (CAS 467457-23-4)
- 2-(4-Dimethylaminophenyl)-1,3-thiazole-4-carboxylic acid (CAS 955400-50-7)
- 2-Boc-8-amino-5-thia-2-azaspiro[3.4]octane-5,5-dioxide (CAS 1340481-83-5)
- 4-(3-Methyl-butyl)-benzenethiol (CAS 5495-73-8)
- 6-Bromo-3-fluoro-2-(fluoromethyl)pyridine (CAS 2069971-69-1)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
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