2-Iodo-1,4-dimethoxybenzene CAS 25245-35-6
| CAS No. | 25245-35-6 |
| Molecular Formula | C8H9IO2 |
| Molecular Weight | 264.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 264.06 g/mol gives 2-Iodo-1,4-dimethoxybenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Iodo-1,4-dimethoxybenzene (CAS 25245-35-6), molecular formula C8H9IO2 and molecular weight 264.06 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Iodo-1,4-dimethoxybenzene (C8H9IO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 264.06 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9IO2 |
| Molecular Weight | 264.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | I-containing |
Related Iodo Standards
- 4-Iodo-N,N-dimethyl-1H-pyrrole-2-carboxamide (CAS 1092352-92-5)
- 2-Iodo-6-isopropoxypyrazine (CAS 125060-56-2)
- 4-Iodo-1-(oxolan-3-yl)-1h-pyrazole (CAS 1344092-28-9)
- 1-(4-Iodo-3-methyl-1H-pyrazol-1-yl)propan-2-one (CAS 1354703-43-7)
- 1-(1-Ethyl-4-iodo-1H-pyrazol-3-yl)ethan-1-one (CAS 1354705-07-9)
- 1-(1-Ethyl-4-iodo-1H-pyrazol-5-yl)ethan-1-one (CAS 1354705-81-9)
- 1-(4-Iodo-5-methyl-1H-pyrazol-1-yl)propan-2-one (CAS 1354705-88-6)
- (2-Iodo-4-methoxyphenyl)methanol (CAS 1379329-63-1)
Recommended Standards
- 2,4-Dimethoxyiodobenzene (CAS 20469-63-0)
- 2-Iodo-6-methoxybenzyl alcohol (CAS 877265-22-0)
- 2-(4-Iodophenoxy)ethan-1-ol (CAS 29639-77-8)
- 3-Iodo-2-methyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-4-ol (CAS 2168559-77-9)
- Benzyl (3-(aminomethyl)oxetan-3-yl)carbamate (CAS 1802048-94-7)
- 2-Methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]isoindole-6,7-diol (CAS 115103-48-5)
- 4-(Dimethylamino)-3-methoxy-4-oxobutanoic acid (CAS 1330755-19-5)
- 3-Bromo-7-chloro-6-iodoquinolin-4-ol (CAS 1021913-04-1)
- 2-(2,2-Dibromoethenyl)-3-methylthiophene (CAS 77386-41-5)
- L-Methionine-(S)-sulfoximine (CAS 21752-32-9)
- 1-(3-Aminopyrrolidin-1-yl)pentan-1-one (CAS 1339442-73-7)
- 1-cyclopentyl-3-(pyridin-4-yl)propan-2-amine dihydrochloride (CAS 1461708-97-3)
- 1-Benzyl-3-nitro-4-phenylpyrrolidine (CAS 1823551-60-5)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
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