4’-Bromo-2’-chloroacetophenone CAS 252561-81-2
| CAS No. | 252561-81-2 |
| Molecular Formula | C8H6BrClO |
| Molecular Weight | 233.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4’-Bromo-2’-chloroacetophenone is closely related to a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4’-Bromo-2’-chloroacetophenone (CAS 252561-81-2), molecular formula C8H6BrClO and molecular weight 233.49 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4’-Bromo-2’-chloroacetophenone (C8H6BrClO) contains a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 233.49 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6BrClO |
| Molecular Weight | 233.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 5-Bromo-4-chloro-2-cyclopropylpyrimidine (CAS 1044767-90-9)
- 5’-Bromo-2’-chloroacetophenone (CAS 105884-19-3)
- 6-Bromo-2-Chloro-3-methylbenzaldehyde (CAS 1114808-98-8)
- 2-Bromo-6-chloro-3-methylbenzaldehyde (CAS 1114809-00-5)
- 121794-40-9 2-bromo-3-methylbenzyl acid chloride (CAS 121794-40-9)
- 4-Bromo-3-chloro-2-methylbenzaldehyde (CAS 1224604-13-0)
- 1-(2-Bromo-6-chlorophenyl)ethan-1-one (CAS 1261438-38-3)
- 7-Bromo-5-chloro-2,3-dihydrobenzofuran (CAS 134402-21-4)
Recommended Standards
- 3-Bromophenylacetyl chloride (CAS 98288-51-8)
- 4’-Bromo-2-chloroacetophenone (CAS 4209-02-3)
- 3-Bromo-4-methyl-benzoyl chloride (CAS 21900-33-4)
- 4-Bromo-2-chloro-1-(vinyloxy)benzene (CAS 869569-67-5)
- Ethyl 4-(4-chlorophenyl)-1H-pyrazole-3-carboxylate (CAS 1198351-56-2)
- Ciliobrevin A (CAS 302803-72-1)
- Potassium (3-((3-bromophenyl)amino)-3-oxopropyl)trifluoroborate (CAS 1705578-20-6)
- 2-Hydroxy-3-methylcholanthrene (CAS 3308-64-3)
- 5,7-Dimethyl-2-(piperidin-4-yl)-3H-imidazo[4,5-b]pyridine (CAS 1355172-73-4)
- tert-Butyl 3-phenylpiperazine-1-carboxylate (CAS 502649-25-4)
- 2-(4-Chlorophenoxy)-1-(piperazin-1-yl)ethan-1-one hydrochloride (CAS 1144037-44-4)
- 2-(3-((Benzyloxy)carbonyl)-3-azabicyclo[3.1.1]Heptan-6-yl)acetic acid (CAS 2231676-30-3)
- Avatrombopag Impurity 144 (CAS CATO-C4X-2234144)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
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