Tert-butyl (3S,4S)-3-bromo-4-hydroxypyrrolidine-1-carboxylate CAS 252574-02-0
| CAS No. | 252574-02-0 |
| Molecular Formula | C9H16BrNO3 |
| Molecular Weight | 266.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tert-butyl (3S,4S)-3-bromo-4-hydroxypyrrolidine-1-carboxylate (C9H16BrNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Tert-butyl (3S,4S)-3-bromo-4-hydroxypyrrolidine-1-carboxylate (CAS 252574-02-0), molecular formula C9H16BrNO3 and molecular weight 266.13 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H16BrNO3 |
| Molecular Weight | 266.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 9-Bromo-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-5-one (CAS 57369-19-4)
- tert-Butyl (4-bromo-3-oxobutyl)carbamate (CAS 207555-89-3)
- 8-Bromo-5-propoxyisoquinoline (CAS 820238-27-5)
- tert-butyl 3-bromo-3-(hydroxymethyl)azetidine-1-carboxylate (CAS 2007919-81-3)
- 2-Bromo-8-chloro-1,7-naphthyridine (CAS 1260666-72-5)
- 5-Methyl-2-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine (CAS 1227210-32-3)
- 2-(4-(Piperidin-1-yl)butoxy)benzaldehyde (CAS 82625-42-1)
- 2-Amino-2-oxoethyl 3,4,5-trihydroxybenzoate hydrate (CAS 495388-60-8)
- Ethyl 2-amino-2-cyclohexylacetate hydrochloride (CAS 327052-06-2)
- Bis(trimethylsilyl)methylamine (CAS 134340-00-4)
- 5-Cyano-2-fluorobenzeneboronic acid (CAS 468718-30-1)
- rel-((3R,7aR)-3-(methoxymethyl)hexahydro-1H-pyrrolizin-7a-yl)methanol (CAS 2621937-89-9)
- Roxadustat Impurity 175 (CAS CATO-C4X-2213175)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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