(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite CAS 252770-65-3
| CAS No. | 252770-65-3 |
| Molecular Formula | C40H47FN7O6P |
| Molecular Weight | 771.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 252770-65-3), a certified reference material (molecular formula C40H47FN7O6P, MW 771.82 g/mol) for analytical method development and quality control.
(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (C40H47FN7O6P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C40H47FN7O6P |
| Molecular Weight | 771.82 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Recommended Standards
- Palbociclib Impurity 165 (CAS CATO-C4X-1125165)
- Palbociclib Lactose adduct 1 (CAS CATO-C4X-112561)
- Palbociclib Impurity 143 (CAS CATO-C4X-1125143)
- Palbociclib Lactose adduct 2 (CAS CATO-C4X-112562)
- Ethoxymethyl propionate (CAS 54078-53-4)
- n-(Furan-2-ylmethyl)-2-methylcyclohexan-1-amine (CAS 355381-97-4)
- 2-(tert-Butoxycarbonyl)-2-azabicyclo[4.1.0]heptane-7-carboxylic acid (CAS 1251019-95-0)
- 2-Methyl-2-azaspiro[3.3]heptan-6-amine (CAS 2081079-38-9)
- (S)-3-amino-4-(3,4-dichlorophenyl)butanoic acid hydrochloride (CAS 270063-50-8)
- 3-(4-Fluoro-2-methylphenyl)-3-hydroxypropanenitrile (CAS 1510168-67-8)
- Ethyl 4H-1,2,4-triazole-4-carboxylate (CAS 83784-81-0)
- Methyl 2-(6-Fluoro-3-indolyl)-2-oxoacetate (CAS 345265-51-2)
- 2-Butoxyethyl Bromide, Pract. 6550-99-8 2-Bromoethyl Butyl Ether, Pract. (CAS 6550-99-8)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com