5-Chloro-1-methyl-1H-benzo[d][1,2,3]triazole CAS 25299-32-5
| CAS No. | 25299-32-5 |
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-1-methyl-1H-benzo[d][1,2,3]triazole.
5-Chloro-1-methyl-1H-benzo[d][1,2,3]triazole (CAS 25299-32-5) is a high-purity analytical reference standard with the molecular formula C7H6ClN3 and a molecular weight of 167.60 g/mol.
The molecular framework of 5-Chloro-1-methyl-1H-benzo[d][1,2,3]triazole (C7H6ClN3) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- 5-chloro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 936243-40-2)
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- 5-Chloro-1H-indazol-7-amine (CAS 221681-89-6)
- 5-Chloro-3-methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 66999-59-5)
- Methyl 3-oxo-4-(4-trifluoromethylphenyl)butanoate (CAS 1048916-84-2)
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- 2-Amino-4-(4-hydroxyphenyl)butanoic acid (CAS 185062-84-4)
- 4-[ethyl(methyl)amino]benzaldehyde (CAS 64693-47-6)
- 5-Fluoro-2-(3-fluorophenyl)pyridine 1-oxide (CAS 1700602-74-9)
- 2-Iodo-3-methyl-5-(trifluoromethyl)phenol (CAS 2055497-48-6)
- 5-(4-Chlorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine (CAS 67200-28-6)
- 1H-indol-5-yl acetate (CAS 5594-91-2)
- (6-Methoxynaphthalen-2-yl)(phenyl)methanone (CAS 84255-35-6)
- Semaglutide Impurity 143 (CAS CATO-C4X-2226143)
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