5,5'-Methylenebis(quinolin-8-ol) CAS 2536-71-2
| CAS No. | 2536-71-2 |
| Molecular Formula | C19H14N2O2 |
| Molecular Weight | 302.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5,5'-Methylenebis(quinolin-8-ol) (CAS 2536-71-2), molecular formula C19H14N2O2 and molecular weight 302.33 g/mol, is a CATO reference standard with documented purity and traceability.
5,5'-Methylenebis(quinolin-8-ol) (C19H14N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H14N2O2 |
| Molecular Weight | 302.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Methylenebis Standards
- 4,4'-(Methylenebis(1,3-dioxolane-2,4-diyl))bis(butan-1-ol) (CAS 5570-66-1)
- 1,1'-Methylenebis(indoline-2,3-dione) (CAS 54790-42-0)
- 2,2′-Methylenebis[4,5-dihydro-4-phenyloxazole] (CAS 233276-14-7)
- 2,2'-Methylenebis-(4-chloro-6-methyl-phenol) (CAS 57693-35-3)
- (Methylenebis(1H-benzo[d]imidazole-6,2-diyl))dimethanol (CAS 294656-32-9)
- 4,4'-Methylenebis(N,N-diethylaniline) (CAS 135-91-1)
- 4,4'-Methylenebis(2-Isopropyl-6-Methyllaniline) (CAS 16298-38-7)
- 4,4'-Methylenebis(N-(sec-butyl)aniline) (CAS 5285-60-9)
Recommended Standards
- 5-(4-Hydroxybenzyl)-3-(2-hydroxyphenyl)imidazolidine-2,4-dione (CAS 20852-40-8)
- 5-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-1H-1,2,4-triazol-3-amine (CAS 477851-41-5)
- 4-Methyl-1,3-diphenylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 30020-86-1)
- 5-Methyl-3,6-diphenylisoxazolo[4,5-c]pyridin-4(5H)-one (CAS 60986-80-3)
- 2-Hydrazinyl-3,7-dimethylquinoline hydrochloride (CAS 1170974-94-3)
- 2-Bromo-4-(2-fluoroethoxy)pyridine (CAS 1802415-24-2)
- 3-Ethyl-4-phenylazetidin-2-one (CAS 180324-53-2)
- 2-Chloro-3-(difluoromethyl)-6-(trifluoromethyl)pyridin-4-ol (CAS 1805993-81-0)
- tert-Butyl (R)-3-(2,6-difluorobenzyl)piperazine-1-carboxylate (CAS 1240586-01-9)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1002460-75-4)
- Ethyl (S)-3-(4-aminophenyl)-2-(1,3-dioxoisoindolin-2-yl)propanoate hydrochloride (CAS 97338-03-9)
- (S)-2-amino-3-(3-methoxyphenyl)propan-1-ol (CAS 938462-27-2)
- 3-((4-Bromophenyl)thio)-1-(4-hydroxyphenyl)propan-1-one (CAS 882748-46-1)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
Why CATO?
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