N-Methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine CAS 25366-22-7
| CAS No. | 25366-22-7 |
| Molecular Formula | C4H4F3N3S |
| Molecular Weight | 183.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-Methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine (C4H4F3N3S) contains a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies N-Methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine (CAS 25366-22-7), a certified reference material (molecular formula C4H4F3N3S, MW 183.15 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-Methyl-5-(trifluoromethyl)-1,3,4-thiadiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4F3N3S |
| Molecular Weight | 183.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- N-(3,4-difluorophenyl)acrylamide (CAS 519004-33-2)
- 2-[3-(difluoromethoxy)phenyl]acetonitrile 2-[3-[bis(fluoranyl)methoxy]phenyl]ethanenitrile 41429-18-9 A825551 (CAS 41429-18-9)
- 6-(Difluoromethoxy)-1H-indole (CAS 200207-21-2)
- Methyl 5-[(hydroxyimino)methyl]-2-methylfuran-3-carboxylate (CAS 1000932-97-7)
- Methyl 2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-6-carboxylate (CAS 1779729-77-9)
- 1-(Difluoromethyl)-4-(trifluoromethyl)benzene (CAS 2251-82-3)
- 2-Amino-4-(difluoromethyl)-5-nitronicotinonitrile (CAS 1803670-23-6)
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Why CATO?
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