Kanamycin A Sulfate (Amikacin EP Impurity D Sulfate) CAS 25389-94-0
| CAS No. | 25389-94-0 |
| Molecular Formula | C18H36N4O11 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 582.58 g/mol gives Kanamycin A Sulfate (Amikacin EP Impurity D Sulfate) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Kanamycin A Sulfate (Amikacin EP Impurity D Sulfate) (CAS 25389-94-0, C18H36N4O11H2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Kanamycin A Sulfate (Amikacin EP Impurity D Sulfate) (C18H36N4O11H2O4S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 582.58 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H36N4O11 H2O4S |
| Molecular Weight | 582.58 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Kanamycin Standards
Recommended Standards
- Olmesartan Impurity 43 (CAS 1227664-85-8)
- Relugolix Impurity 169 (CAS CATO-C4X-2429169)
- Baloxavir Impurity 27 (CAS 2762066-94-2)
- 25114-58-3 5-tert-butyl-4-({6-hydroxy-2-[2-(4-hydroxyphenyl)ethyl]-4-oxo-2-(propan-2-yl)-3,4-dihydro-2h-pyran-5-yl}sulfanyl)-2-methylphenyl dimethylsulfamate AR-1G9533 (CAS 25114-58-3)
- Naphthalene-2,6-diylbis((2,6-dimethylnaphthalen-1-yl)methanone) (CAS 157585-49-4)
- Isavuconazole Impurity 119 (CAS CATO-C4X-1236119)
- N-(3-Amino-4-chlorophenyl)-2-methoxyacetamide (CAS 926265-38-5)
- N-[2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide (CAS 1112983-31-9)
- (1E)-1-(5-Chloro-2-phenyl-1H-imidazol-4-yl)-N-(4-chlorophenyl)methanimine (CAS 860787-98-0)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com