ethyl 4-chloro-8-methyl-6-prop-1-ynyl-quinoline-3-carboxylate CAS 2543159-46-0
| CAS No. | 2543159-46-0 |
| Molecular Formula | C16H14ClNO2 |
| Molecular Weight | 287.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
ethyl 4-chloro-8-methyl-6-prop-1-ynyl-quinoline-3-carboxylate (CAS 2543159-46-0) is a high-purity analytical reference standard with the molecular formula C16H14ClNO2 and a molecular weight of 287.74 g/mol.
The molecular framework of ethyl 4-chloro-8-methyl-6-prop-1-ynyl-quinoline-3-carboxylate (C16H14ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures ethyl 4-chloro-8-methyl-6-prop-1-ynyl-quinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClNO2 |
| Molecular Weight | 287.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Diazepam Impurity 12 (CAS 36271-03-1)
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- 3-(Trifluoromethyl)quinoline-2-carboxylic acid (CAS 588702-64-1)
- 3-Isopropoxy-N-((1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)propan-1-amine hydrochloride (CAS 1856073-09-0)
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- Ethyl 3-phenyl-5-(o-tolylthio)-1,2,4-triazine-6-carboxylate (CAS 338957-17-8)
- 1-(Tetrahydro-2H-pyran-4-ylcarbonyl)-4-piperidinecarboxylic acid (CAS 1042796-19-9)
- Relebactam Impurity 27 (CAS CATO-C4X-214427)
- 1-(6-Ethylpyridin-3-yl)ethan-1-one (CAS 1211536-35-4)
- 4-((6-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-3,5-difluoroaniline (CAS 1203656-90-9)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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