4-Chloro-6β,17β-dihydroxy-17α-methyl-1,4-androstadien-3-one CAS 25486-01-5

Description

As a certified reference material (CRM), 4-Chloro-6β,17β-dihydroxy-17α-methyl-1,4-androstadien-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

4-Chloro-6β,17β-dihydroxy-17α-methyl-1,4-androstadien-3-one (CAS 25486-01-5) is a high-purity analytical reference standard with the molecular formula C20H27ClO3 and a molecular weight of 350.88 g/mol.

4-Chloro-6β,17β-dihydroxy-17α-methyl-1,4-androstadien-3-one (C20H27ClO3) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

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