3-amino-1-chloro-4-phenylbutan-2-one CAS 25487-25-6
| CAS No. | 25487-25-6 |
| Molecular Formula | C10H12ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 278.57 g/mol gives 3-amino-1-chloro-4-phenylbutan-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-amino-1-chloro-4-phenylbutan-2-one (CAS 25487-25-6), a certified reference material (molecular formula C10H12ClNOHBr, MW 278.57 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H12ClNOHBr, 3-amino-1-chloro-4-phenylbutan-2-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 278.57 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO HBr |
| Molecular Weight | 278.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related amino Standards
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- Methyl 2-amino-5-bromo-4-isopropylbenzoate (CAS 1000018-13-2)
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- 100005-23-0 2-Amino-4-(4-methoxyphenyl)-5-methylthiophene-3-carbonitrile 7050AC C13H12N2OS (CAS 100005-23-0)
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- 6-Amino-7-hydroxy-2,3-dihydro-1H-inden-1-one hydrobromide (CAS 1000333-87-8)
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Recommended Standards
- Ethyl 4-(4-methoxyphenyl)-3-oxobutanoate (CAS 32711-91-4)
- (E)-2-Acetoxy-2-bromo-5-chlorostilbene (CAS 1000890-01-6)
- 2-Amino-5-isobutyl-4-oxo-4,5-dihydro-1h-pyrrole-3-carbonitrile (CAS 929974-28-7)
- Acibenzolar Acid Impurity 8 (CAS 124371-49-9)
- Bedaquiline Impurity 1 (CAS 349537-52-6)
- 2-(2-(Bromomethyl)phenyl)pyridine (CAS 184889-81-4)
- 2-((4-Allyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-isopropylphenyl)acetamide (CAS 585557-33-1)
- (2-Chloro-5-(difluoromethyl)-4-fluoropyridin-3-yl)methanol (CAS 1806914-17-9)
- 4-(4-hydroxyphenoxy)-3-methylbenzamide (CAS 1179251-46-7)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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