4-((4-Bromo-2-fluorobenzyl)oxy)benzaldehyde CAS 255832-77-0
| CAS No. | 255832-77-0 |
| Molecular Formula | C14H10BrFO2 |
| Molecular Weight | 309.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((4-Bromo-2-fluorobenzyl)oxy)benzaldehyde.
4-((4-Bromo-2-fluorobenzyl)oxy)benzaldehyde (CAS 255832-77-0) is a high-purity analytical reference standard with the molecular formula C14H10BrFO2 and a molecular weight of 309.13 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, a polycyclic aromatic system, 4-((4-Bromo-2-fluorobenzyl)oxy)benzaldehyde is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 309.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((4-Bromo-2-fluorobenzyl)oxy)benzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10BrFO2 |
| Molecular Weight | 309.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 5-Bromo-3-fluoro-2-(phenylmethoxy)benzaldehyde, (CAS 1003298-75-6)
- n-(4-Bromo-2-fluorophenyl)-6-methylnicotinamide (CAS 1016706-44-7)
- 2-Bromo-4-fluoro-N-(pyridin-2-ylmethyl)benzamide (CAS 1017054-90-8)
- 2-Bromo-4-fluoro-N-(4-methylpyridin-2-yl)benzamide (CAS 1019126-57-8)
- 2-Bromo-5-fluoro-N-(pyridin-4-ylmethyl)benzamide (CAS 1036547-07-5)
- 2-Bromo-5-fluoro-N-(pyridin-3-ylmethyl)benzamide (CAS 1036600-66-4)
- 4-Bromo-2-fluoro-N-(pyridin-4-ylmethyl)benzamide (CAS 1040084-38-5)
- 4-Bromo-2-fluoro-N-(pyridin-3-ylmethyl)benzamide (CAS 1041573-62-9)
Recommended Standards
- 3-Bromo-4-[(4-fluorobenzyl)oxy]benzaldehyde (CAS 428484-82-6)
- 4'-(2-Bromo-4-fluorophenoxy)acetophenone (CAS 845866-51-5)
- 3-Bromo-4-((2-fluorobenzyl)oxy)benzaldehyde (CAS 428497-60-3)
- 4-Bromo-2-fluoro-N-(6-methylpyridin-2-yl)benzamide (CAS 391223-01-1)
- Methyl 6-chloro-1-oxoisochromane-3-carboxylate (CAS 951896-50-7)
- 1-Methylimidazole Hydrobromide (CAS 101023-58-9)
- 2-Amino-3-(2-hydroxy-3-methoxyphenyl)propanoic acid (CAS 98758-16-8)
- 2-Phenyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 55643-77-1)
- 2-(3-(4-Fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl)acetonitrile (CAS 478041-35-9)
- 3-Bromoisoxazolo[5,4-b]pyridine (CAS 864872-31-1)
- Tetramethyldiacetoxystannoxane (CAS 5926-79-4)
- 3-Ethyl-2-(5-(3-ethyl-1,1-dimethyl-1H-benzo[e]indol-2(3H)-ylidene)penta-1,3-dien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium iodide (CAS 123791-69-5)
- 5-(2-Methoxyethoxy)pyridin-2-amine (CAS 1019583-54-0)
- ([D2]Gly4)-Cholecystokinin Octapeptide (sulfated) ammonium salt (CAS 1926163-74-7)
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