N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide CAS 256458-69-2
| CAS No. | 256458-69-2 |
| Molecular Formula | C16H10BrFN2O2 |
| Molecular Weight | 361.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 361.17 g/mol gives N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide (CAS 256458-69-2), a certified reference material (molecular formula C16H10BrFN2O2, MW 361.17 g/mol) for analytical method development and quality control.
N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide (C16H10BrFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N1-(4-fluorophenyl)-2-(5-bromo-1H-indol-3-yl)-2-oxoacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10BrFN2O2 |
| Molecular Weight | 361.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- Ethyl 3-[2-(4-fluorophenyl)-4-methyl-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl]-1,2,4-oxadiazole-5-carboxylate (CAS 933219-93-3)
- 5-(4-Fluorophenyl)-2,4-dihydroxy-5,11-dihydro-6H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidin-6-one (CAS 433693-72-2)
- 2,4,6-Tris(4-fluorophenyl)pyridine (CAS 41855-53-2)
- Methyl 1-(2-fluorophenyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011400-05-7)
- 1-(3-Fluorophenyl)-6-methyl-3-(quinolin-2-ylmethoxy)pyridazin-4(1H)-one (CAS 146824-87-5)
- 1-(4-Fluorophenyl)-6-methyl-3-(quinolin-2-ylmethoxy)pyridazin-4(1H)-one (CAS 146824-88-6)
- N-[(4-Fluorophenyl)methyl]-2-[2-(pyridin-2-yl)-1,3-benzoxazol-5-yl]acetamide (CAS 866041-10-3)
- 4-(2-Fluorophenyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 728012-89-3)
Recommended Standards
- 4-(Bromodifluoromethyl)-3,5-difluoro-4'-propyl-1,1'-biphenyl (CAS 595607-78-6)
- Sucralose EP Impurity F (CAS 61854-83-9)
- 3-(6-Bromo-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-42-8)
- Sucralose EP Impurity G (CAS 105066-20-4)
- 1,3,3-trimethylpiperidin-4-amine (CAS 1369161-64-7)
- Tert-butyl (3R,5S)-3-methyl-5-(pyridin-3-yl)piperazine-1-carboxylate (CAS 1557288-59-1)
- (4S,5S)-1,3-Dibenzyl-4,5-diphenyl-1,3,2-diazaphospholidine 2-oxide (CAS 138421-34-8)
- 4-(3-(4-Nitrobenzyl)ureido)benzene-1-sulfonyl fluoride (CAS 21315-99-1)
- 2-(Aminomethyl)-6-cyano-3-(difluoromethyl)-5-iodopyridine (CAS 1804730-53-7)
- 3,4-dimethyl-benzeneacetic acid methyl ester (CAS 57486-71-2)
- 1-(2-Chloro-6-methylpyrimidin-4-yl)ethanone (CAS 2352655-69-5)
- Gefitinib Impurity 8 (CAS 847949-49-9)
- 3-Amino-2,2-dimethylpropanenitrile hydrochloride (CAS 1196693-40-9)
- Tirzepatide Impurity 36 (CAS CATO-C4X-324036)
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