1,4-Bis(4-fluorophenyl)but-2-ene-1,4-dione CAS 25650-13-9
| CAS No. | 25650-13-9 |
| Molecular Formula | C16H10F2O2 |
| Molecular Weight | 272.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1,4-Bis(4-fluorophenyl)but-2-ene-1,4-dione (CAS 25650-13-9) is a high-purity analytical reference standard with the molecular formula C16H10F2O2 and a molecular weight of 272.25 g/mol.
The molecular framework of 1,4-Bis(4-fluorophenyl)but-2-ene-1,4-dione (C16H10F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10F2O2 |
| Molecular Weight | 272.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | F-containing |
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Recommended Standards
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- (2R,3R)-3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chroman-4-one (CAS 55812-91-4)
- 4-(2-Methyl-2h-tetrazol-5-yl)phenol (CAS 81015-02-3)
- JWH-203 N-pentanoic acid metabolite (CAS 1449675-70-0)
- 2-Benzoyl-4-chlorobenzenesulfonyl chloride (CAS 19562-55-1)
- (R)-6,6-Dimethylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione (CAS 2165780-97-0)
- 6-methyl-2-(propylamino)-3,4-dihydroquinazolin-4-one (CAS 1015479-08-9)
- tert-Butyl 2-(((4-methylpyridin-2-yl)thio)methyl)piperidine-1-carboxylate (CAS 1353979-19-7)
- [(2R,3S,5R)-2-Cyano-5-(5-Fluoro-2,4-Dioxo-Pyrimidin-1-ylOxolan-3-Yl] Acetate (CAS 54918-13-7)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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