2,2,6,6-Tetramethyl-1-(prop-2-yn-1-yl)piperidine CAS 25665-47-8
| CAS No. | 25665-47-8 |
| Molecular Formula | C12H21N |
| Molecular Weight | 179.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,2,6,6-Tetramethyl-1-(prop-2-yn-1-yl)piperidine (C12H21N) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2,2,6,6-Tetramethyl-1-(prop-2-yn-1-yl)piperidine (CAS 25665-47-8), molecular formula C12H21N and molecular weight 179.30 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H21N |
| Molecular Weight | 179.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1964 |
| Nitrogen Atoms | 1 |
Related Tetramethyl Standards
- 1,1,3,3-Tetramethyl-2,3,3a,4-tetrahydrocyclopenta[c]pyrrol-5(1H)-one (CAS 104668-23-7)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propanenitrile (CAS 238088-31-8)
- (E)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)acrylaldehyde (CAS 153725-01-0)
- 4,4,5,5-Tetramethyl-2-(1-methylcyclopropyl)-1,3,2-dioxaborolane (CAS 126689-04-1)
- 4,4,5,5-tetramethyl-2-[cis-2-methylcyclopropyl]-1,3,2-dioxaborolane (CAS 1309366-00-4)
- Rac-4,4,5,5-tetramethyl-2-[(1r,2r)-2-methylcyclopropyl]-1,3,2-dioxaborolane, trans (CAS 1350713-20-0)
- 4,4,5,5-Tetramethyl-2-(2-methylallyl)-1,3,2-dioxaborolane (CAS 167773-10-6)
- 4,4,5,5-Tetramethyl-2-((1R,2S)-2-methylcyclopropyl)-1,3,2-dioxaborolane (CAS 1813575-99-3)
Recommended Standards
- 2-(Adamantan-2-yl)ethan-1-amine (CAS 59807-53-3)
- 2,2-Bis-(2-methyl-allyl)-pyrrolidine (CAS 282089-89-8)
- 2-(Adamantan-1-yl)ethan-1-amine (CAS 26482-53-1)
- 2,2-Bis(ethylthio)acetamide (CAS 89450-18-0)
- 5-Bromo-3-(pyrrolidin-1-yl)pyridin-2-amine (CAS 1335051-44-9)
- Azido-PEG8-hydrazide (CAS 2353410-11-2)
- 2-(3-Acetoxybenzoyl) thiophene (CAS 106882-29-5)
- Ethyl 2-amino-4-(4-chlorophenyl)-5-methylthiophene-3-carboxylate (CAS 350989-77-4)
- 3,5-Dimethyl-1-((3-(trifluoromethyl)phenoxy)methyl)-1h-pyrazol-4-amine (CAS 956396-71-7)
- 1-(5-(Diethylamino)-4-ethyl-2-methyl-4,5-dihydrofuran-3-yl)ethanone (CAS 88557-07-7)
- 2-fluoro-4-nitrobenzene-1-sulfonamide (CAS 1204574-82-2)
- Valsartan Impurity 56 HCl (CAS 482577-59-3)
- (4-Fluoro-5-methylthiophen-2-yl)(naphthalen-1-yl)methanol (CAS 1443310-08-4)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com