2-Cyclopropyl-5-methylthiophen-3-amine hydrochloride CAS 2567560-68-1
| CAS No. | 2567560-68-1 |
| Molecular Formula | C8H11NS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Cyclopropyl-5-methylthiophen-3-amine hydrochloride (CAS 2567560-68-1), molecular formula C8H11NSHCl and molecular weight 189.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Cyclopropyl-5-methylthiophen-3-amine hydrochloride (C8H11NSHCl) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11NS HCl |
| Molecular Weight | 189.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ethyl 1-Benzylpyrazole-3-carboxylate (CAS 174907-58-5)
- 2-Hydroxy-6-(trifluoromethyl)nicotinaldehyde (CAS 1227602-74-5)
- 1-(Tetrahydrofuran-2-yl)butane-1,3-dione (CAS 860705-06-2)
- 6,8-Dimethyl-1H-pyrido[2,3-b][1,4]thiazin-2(3H)-one (CAS 889943-35-5)
- 6-Chloro-2-propyl-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridine (CAS 1018165-58-6)
- Octyl D-galactofuranoside (CAS 202403-49-4)
- 2-(Pyrimidin-2-yl)benzenesulfonamide (CAS 88152-97-0)
- 2-(4-Methylpiperazin-1-yl)-4-(trifluoromethyl)benzaldehyde (CAS 857263-88-8)
- 3-(Aminomethyl)-1H-indazole (CAS 806640-37-9)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
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