3alpha-Hydroxy-4-pregnen-20-one CAS 25680-68-6
| CAS No. | 25680-68-6 |
| Molecular Formula | C21H32O2 |
| Molecular Weight | 316.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3alpha-Hydroxy-4-pregnen-20-one (CAS 25680-68-6) is a high-purity analytical reference standard with the molecular formula C21H32O2 and a molecular weight of 316.48 g/mol.
Owing to a steroid core, a hydroxyl group, an ether linkage, 3alpha-Hydroxy-4-pregnen-20-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 316.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H32O2 |
| Molecular Weight | 316.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
Related alpha Standards
- N1-(2-Hydroxy-2-methyl-4-(methylthio)butyl)-N2-(thiophen-2-ylmethyl)oxalamide (CAS 1396774-48-3)
- 17β-Hydroxy-5α-androstano[2,3-c]furazan (CAS 3662-95-1)
- (5α,16α)-16-Hydroxy-1-methyl-androst-1-ene-3,17-dione (CAS 132309-88-7)
- Rac 4-Hydroxy-9-cis-retinoic Acid (CAS 150737-17-0)
- 18-Hydroxy-all-trans-Retinoic Acid (CAS 63531-93-1)
- 4-Hydroxy-all-trans-Retinoic Acid (CAS 66592-72-1)
- (Z)-4-(4-Hydroxy-1,2-diphenylbut-1-en-1-yl)phenol (CAS 89778-37-0)
- 6'-Hydroxy Secophenol (CAS 2168-61-8)
Recommended Standards
- 2,3-Dihydroxypropyl pentadecanoate (CAS 62927-08-6)
- 4-((4-Chlorobenzyl)thio)-6,7-dimethoxycinnoline (CAS 5387-86-0)
- 16, (5β)-PREGNEN-3β-OL-20-ONE (CAS 566-59-6)
- 4-(3-methoxypropyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 568555-38-4)
- Methyl 2,3,5-trifluoro-4-(piperidin-1-yl)benzoate (CAS 1858249-59-8)
- 3,4-Dichloro-4-(ethylthio)benzophenone (CAS 844885-36-5)
- Methyl 2-amino-7,7-dimethyl-4-(3-nitrophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 303953-38-0)
- 5-Bromophthalazine (CAS 103119-78-4)
- N-((1-methyl-1H-indol-2-yl)methyl)cyclopropanamine (CAS 335031-67-9)
- 2-(6-Bromo-2-naphthalenyl)-4,5-dihydro-4,4-dimethyloxazole (CAS 337524-03-5)
- 4-(2-Amino-2-oxoethoxy)-3-chlorobenzoic acid (CAS 1004687-82-4)
- Tetracaine Related Compound 1 (CAS 131719-63-6)
- (3-Bromophenyl)(2-((pyridin-3-ylmethyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 851807-63-1)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com